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Itraconazole vs Terconazole

What each one is for, how to take it, side effects and warnings, side by side from the official labels.

ItraconazoleTerconazole
What it isAn antifungalAn antifungal
Used foris indicated for the treatment of the following fungal infections in immunocompromised and non-immunocompromised adult patients: Blastomycosis, pulmonary and extrapulmonary Histoplasmosis, including chronic cavitary pulmonary disease and disseminated, non-meni…Terconazole vaginal cream 0.4% is indicated for the local treatment of vulvovaginal candidiasis (moniliasis). As terconazole vaginal cream 0.4% is effective only for vulvovaginitis caused by the genus Candida , the diagnosis should be confirmed by KOH smears a…
ChildrenSafety and efficacy in children have not been established.
Prescription (U.S.)YesYes
Common side effectsThe following clinically significant adverse reactions are described elsewhere in the labeling: Congestive Heart Failure [see Warnings and Precautions (5.1) ] Hepatotoxicity [see Warnings and Precautions (5.2) ] Cardiac Dysrhythmi…Adverse Reactions from Clinical Trials Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical tr…
Serious warningand DRUG INTERACTIONS WARNING: CONGESTIVE HEART FAILURE and DRUG INTERACTIONS See full prescribing information for complete boxed warning. Congestive Heart Failure TOLSURA can cause or exacerbate cong…Not on the label
Pregnancy8.1 Pregnancy Risk Summary There are no data on exposure to itraconazole during pregnancy for the approved indications. Published epidemiologic studies of women exposed to short courses of treatment w…Pregnancy Teratogenic Effects, Pregnancy Category C: There was no evidence of teratogenicity when terconazole was administered orally up to 40 mg/kg/day (100x the intravaginal human dose of the 0.4% v…

From the official U.S. labels. Brands and strengths differ between countries.

Can you take them together?

Neither official label mentions the other. That does not prove they are safe together: ask a pharmacist, and use the free interaction checker.

Check them together

Questions

What is the difference between Itraconazole and Terconazole?

Itraconazole is an antifungal and Terconazole is an antifungal. Itraconazole is used for: is indicated for the treatment of the following fungal infections in immunocompromised and non-immunocompromised adult patients: Blastomycosis, pulmonary and extrapulmonary Histoplasmosis, including chronic cavitary pulmonary disease and disseminated, non-meni… Terconazole is used for: Terconazole vaginal cream 0.4% is indicated for the local treatment of vulvovaginal candidiasis (moniliasis). As terconazole vaginal cream 0.4% is effective only for vulvovaginitis caused by the genus Candida , the diagnosis should be confirmed by KOH smears a…

Can I take Itraconazole and Terconazole together?

Neither official label mentions the other. That does not prove they are safe together: ask a pharmacist, and use the free interaction checker.

Which is better, Itraconazole or Terconazole?

It depends on what you are treating, your health and other medicines. Your doctor or pharmacist can tell you which one suits you; this page shows what each official label says.