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Cycloserine

Cycloserine is indicated in the treatment of active pulmonary and extrapulmonary tuberculosis (including renal disease) when the causative organisms a.

ز - الأدوية التي تصرف بموجب وصفة طبية Oral Safety alerts on record

How to use Cycloserine

ما تقوله النشرة الرسمية. إذا وصفه لك طبيب، فاتبع الوصفة. وإذا اختلفت نشرة عبوتك، فالأولوية لها.

لمن هو

Cycloserine is indicated in the treatment of active pulmonary and extrapulmonary tuberculosis (including renal disease) when the causative organisms are susceptible to this drug and when treatment with the primary medications (streptomycin, isoniazid, rifampin, and ethambutol) has proved inadequate. Like all antituberculosis drugs, cycloserine should be administered in conjunction with other effective chemotherapy and not as the sole therapeutic agent. Cycloserine may be effective in the treatment of acute urinary tract infections caused by susceptible strains of gram-positive and gram- negative bacteria. …

كيف يُتناول وكم مرة
  • Cycloserine is effective orally and is currently administered only by this route
  • The usual dosage is 500 mg to 1 g daily in divided doses monitored by blood levels. 1 The initial adult dosage most frequently given is 250 mg twice daily at 12-hour intervals for the first 2 weeks
  • A daily dosage of 1 g should not be exceeded
Talk to a doctor first if

Administration is contraindicated in patients with any of the following: • Hypersensitivity to cycloserine • Epilepsy • Depression, severe anxiety, or psychosis • Severe renal insufficiency • Excessive concurrent use of alcoho

Warnings

Administration of cycloserine should be discontinued or the dosage reduced if the patient develops allergic dermatitis or symptoms of CNS toxicity, such as convulsions, psychosis, somnolence, depression, confusion, hyperreflexia, headache, tremor, vertigo paresis, or dysarthria. The toxicity of cycloserine is closely related to excessive blood levels (above 30 mcg/mL), as determined by high dosage or inadequate renal clearance. The ratio of toxic dose to effective dose in tuberculosis is small. The risk of convulsions is increased in chronic alcoholics. Patients should be monitored by hematologic, renal excretion, blood level, and liver function studies.

الآثار الجانبية المحتملة

Most adverse reactions occurring during therapy with cycloserine involve the nervous system or are manifestations of drug hypersensitivity. The following side effects have been observed in patients receiving cycloserine: Nervous system symptoms (which appear to be related to higher dosages of the drug, i.e., more than 500 mg daily) • Convulsions • Drowsiness and somnolence • Headache • Tremor • Dysarthria • Vertigo • Confusion and disorientation with loss of memory • Psychoses, possibly with suicidal tendencies • Character changes • Hyperirritability • Aggression • Paresis • Hyperreflexia • Paresthesia • Major & minor (localized) clonic seizures • Coma Cardiovascular: Sudden development of c …

If you take too much

Signs and Symptoms: Acute toxicity from cycloserine can occur if more than 1 g is ingested by an adult. Chronic toxicity from cycloserine is dose related and can occur if more than 500 mg is administered daily. The central nervous system is the most common organ system involved with toxicity. Toxic effects may include headache, vertigo, confusion, drowsiness, hyperirritability, paresthesias, dysarthria, psychosis paresis, convulsions, and coma. …

إذا نسيت جرعة

تناولها عندما تتذكر، إلا إذا اقترب موعد الجرعة التالية. عندها تخطَّ الجرعة المنسية. لا تتناول جرعتين معًا أبدًا للتعويض. راجع النشرة، فبعض الأدوية مختلفة.

From the official U.S. FDA label for this active ingredient. Your pack may have a different strength, so always read its leaflet. If a doctor prescribed it, follow the prescription. Ask a pharmacist if you are unsure. Label dated 2024-07-30.

الأسماء التجارية حول العالم

Products with Cycloserine as the active ingredient. Names differ between countries.

Registered products

United States (FDA)

CycloserineCYCLOSERINE 1 kg/kg · Powder · Macleods Pharmaceuticals Limited
NDC 33342-600Label
D-cycloserineCYCLOSERINE 1 g/g · Powder · DARMERICA, LLC
NDC 71052-076Label
CycloserineCYCLOSERINE 250 mg/1 · Capsule · Dr. Reddys Laboratories, Inc.
NDC 43598-235Label
CycloserineCYCLOSERINE .5 kg/.5kg · Powder · Professional Compounding Centers of America
NDC 51927-5276Label
CycloserineCYCLOSERINE 1 kg/kg · Powder · Solara Active Pharma Sciences Limited
NDC 72643-027Label

Nigeria (NAFDAC)

NAFDACCycloserine Capsules USP 250 mg A4-100095

Other countries: check your pack's registration number and we point you to your regulator.

Safety alerts and recalls

D-Cycloserine active pharmaceutical ingredient packaged in varying grams or kg in bags or drums, Attix Pharmaceuticals, 184 Front Street East, Unit 801, Toronto, Ontario M5A 4N3, CU.S. FDA Class II
14 Nov 2014 · Attix Pharmaceuticals · TerminatedPenicillin Cross Contamination: All lots of all products repackaged and distributed between 01/05/12 and 02/12/15 are being recalled because they were repackaged in a facility with penicillin products without adequate separation which could introduce the poten

A recall usually affects certain batches only. Compare the lot number on your pack.

Check your pack of Cycloserine

أو التقط صورًا للعبوة
تبقّت 3 عمليات تحقق مجانية اليوم المصادر الرسمية: FDA الأمريكية · EMA (الاتحاد الأوروبي) · NAFDAC · تنبيهات منظمة الصحة العالمية

Questions about Cycloserine

What is Cycloserine used for?

Cycloserine is indicated in the treatment of active pulmonary and extrapulmonary tuberculosis (including renal disease) when the causative organisms are susceptible to this drug and when treatment with the primary medications (streptomycin, isoniazid, rifampin, and ethambutol) has proved inadequate. Like all antituberculosis drugs, cycloserine should be administered in conjunction with other effective chemotherapy an (From the official U.S. FDA label.)

How do I take Cycloserine?

Follow your prescription or the leaflet in your pack. The official label says: Cycloserine is effective orally and is currently administered only by this route. The usual dosage is 500 mg to 1 g daily in divided doses monitored by blood levels. 1 The initial adult dosage most frequently given is 250 mg twice daily at 12-hour intervals for the first 2 weeks. A daily dosage of 1 g should not be exceeded.…

Do I need a prescription for Cycloserine?

Usually yes. Cycloserine is a prescription medicine in most countries. Rules differ by country.

What brands contain Cycloserine?

Cycloserine is sold under names such as Seromycin, Cycloserine. Brand names differ between countries.

How can I check that my Cycloserine is genuine?

Scan the registration number on your pack with PillVera (NAFDAC number in Nigeria, NDC in the United States, DIN in Canada), check the expiry date and buy only from licensed pharmacies.