What each one is for, how to take it, side effects and warnings, side by side from the official labels.
| Chloroquine | Hydroxychloroquine | |
|---|---|---|
| Used for | Chloroquine phosphate tablets are indicated for the: Treatment of uncomplicated malaria due to susceptible strains of P. falciparum, P.malariae, P. ovale, and P.vivax . Prophylaxis of malaria in geographic areas where resistance to chloroquine is not present.… | Hydroxychloroquine sulfate is an antimalarial and antirheumatic indicated for the: Treatment of uncomplicated malaria due to Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, and Plasmodium vivax in adult and pediatric patients. ( 1.1 ) Prophylaxis… |
| Usual adult dose | Adult Dose: The dosage for prophylaxis is 500 mg (= 300 mg base) administered once per week on exactly the same day of each week. | Adult and Pediatric Patients : Prophylaxis: Begin weekly doses 2 weeks prior to travel to the endemic area, continue weekly doses while in the endemic area, and continue the weekly doses for 4 weeks after leaving the endemic area: - Adults: 400 mg once a week… |
| Infancia | In infants and children the dosage is preferably calculated by body weight. | Not on the label |
| Prescription (U.S.) | Yes | Yes |
| Common side effects | The following adverse reactions have been identified during post-approval use of chloroquine or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not alway… | The following adverse reactions are described in greater detail in other sections: Cardiomyopathy and Ventricular Arrhythmias [see Warnings and Precautions (5.1) ] Retinal Toxicity [see Warnings and Precautions (5.2) ] Serious Ski… |
| Pregnancy | Not on the label | 8.1 Pregnancy Pregnancy Exposure Registry There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to hydroxychloroquine sulfate during pregnancy. Encourage patients to… |
From the official U.S. labels. Brands and strengths differ between countries.
The official labels mention them together: Chloroquine-resistant malaria chloroquine phosphate tablets are not effective against chloroquine-or hydroxychloroquine-resistant strains of plasmodium species (see clinical pharmacology , microbiology ). Ask a pharmacist before combining them.
Check them togetherChloroquine is a medicine and Hydroxychloroquine is a medicine. Chloroquine is used for: Chloroquine phosphate tablets are indicated for the: Treatment of uncomplicated malaria due to susceptible strains of P. falciparum, P.malariae, P. ovale, and P.vivax . Prophylaxis of malaria in geographic areas where resistance to chloroquine is not present.… Hydroxychloroquine is used for: Hydroxychloroquine sulfate is an antimalarial and antirheumatic indicated for the: Treatment of uncomplicated malaria due to Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, and Plasmodium vivax in adult and pediatric patients. ( 1.1 ) Prophylaxis…
The official labels mention them together: Chloroquine-resistant malaria chloroquine phosphate tablets are not effective against chloroquine-or hydroxychloroquine-resistant strains of plasmodium species (see clinical pharmacology , microbiology ). Ask a pharmacist before combining them.
It depends on what you are treating, your health and other medicines. Your doctor or pharmacist can tell you which one suits you; this page shows what each official label says.