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Levocarnitine

Levocarnitine oral solution is indicated in the treatment of primary systemic carnitine deficiency. In the reported cases, the clinical presentation c.

Checked against the official label · Updated

Prescription medicine Oral

Levocarnitine: quick answers

Used for
Levocarnitine oral solution is indicated in the treatment of primary systemic carnitine deficiency.
Usual adult dose
Adults: The recommended dosage of levocarnitine is 1 to 3 g/day for a 50 kg subject, which is equivalent to 10 to 30 mL/day of levocarnitine oral solution.
Infancia
Infants and children: The recommended dosage of levocarnitine is 50 to 100 mg/kg/day which is equivalent to 0.5 mL/kg/day levocarnitine oral solution.
Prescription
Prescription medicine in the United States; rules differ by country.

From the official label (Dec 2024). Your prescription and pharmacist come first.

How to use Levocarnitine

Lo que dice el prospecto oficial. Si te lo recetó un médico, sigue la receta. Si el prospecto de tu caja es distinto, manda el de tu caja.

Para quién es

Levocarnitine oral solution is indicated in the treatment of primary systemic carnitine deficiency. In the reported cases, the clinical presentation consisted of recurrent episodes of Reye-like encephalopathy, hypoketotic hypoglycemia, and/or cardiomyopathy. Associated symptoms included hypotonia, muscle weakness and failure to thrive. A diagnosis of primary carnitine deficiency requires that serum, red cell and/or tissue carnitine levels be low and that the patient does not have a primary defect in fatty acid or organic acid oxidation (see CLINICAL PHARMACOLOGY ). …

Cómo tomarlo y con qué frecuencia
  • For oral use only
  • Not for parenteral use
  • Adults: The recommended dosage of levocarnitine is 1 to 3 g/day for a 50 kg subject, which is equivalent to 10 to 30 mL/day of levocarnitine oral solution
  • Higher doses should be administered only with caution and only where clinical and biochemical considerations make it seem likely that higher doses will be of benefit
  • Dosage should start at 1 g/day (10 mL/day), and be increased slowly while assessing tolerance and therapeutic response
  • Monitoring should include periodic blood chemistries, vital signs, plasma carnitine concentrations, and overall clinical condition
  • Infants and children: The recommended dosage of levocarnitine is 50 to 100 mg/kg/day which is equivalent to 0.5 mL/kg/day levocarnitine oral solution
  • Higher doses should be administered only with caution and only where clinical and biochemical considerations make it seem likely that higher doses will be of benefit
  • Dosage should start at 50 mg/kg/day, and be increased slowly to a maximum of 3 g/day (30 mL/day) while assessing tolerance and therapeutic response
  • Monitoring should include periodic blood chemistries, vital signs, plasma carnitine concentrations, and overall clinical condition
  • Levocarnitine oral solution may be consumed alone or dissolved in drink or other liquid food
  • Doses should be spaced evenly throughout the day (every three or four hours) preferably during or following meals and should be consumed slowly in order to maximize tolerance
Infancia

See DOSAGE AND ADMINISTRATION .

Talk to a doctor first if

None known.

Medicines it may not mix with

Reports of INR increase with the use of warfarin have been observed. It is recommended that INR levels be monitored in patients on warfarin therapy after the initiation of treatment with levocarnitine or after dose adjustments.

Warnings

Hypersensitivity Reactions Serious hypersensitivity reactions, including rash, urticaria, and facial edema have been reported with oral levocarnitine. Other serious hypersensitivity reactions, including anaphylaxis, laryngeal edema, and bronchospasm have been reported following intravenous levocarnitine administration, mostly in patients with end-stage renal disease undergoing dialysis. Discontinue use of levocarnitine and instruct patients to seek medical attention if they experience symptoms suggestive of a hypersensitivity reaction.

Posibles efectos secundarios

The following adverse reactions associated with the use of oral formulations of levocarnitine were identified in clinical trials or postmarketing reports. Because these reactions were reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency, reliability, or to establish a causal relationship to drug exposure. Gastrointestinal Reactions : Various mild gastrointestinal complaints have been reported during the long-term administration of oral L- or D,L-carnitine; these include transient nausea and vomiting, abdominal cramps, and diarrhea. …

Pregnancy and breastfeeding

Pregnancy Reproductive studies have been performed in rats and rabbits at doses up to 3.8 times the human dose on the basis of surface area and have revealed no evidence of impaired fertility or harm to the fetus due to levocarnitine. There are, however, no adequate and well-controlled studies in pregnant women. …

If you take too much

There have been no reports of toxicity from levocarnitine overdosage. Levocarnitine is easily removed from plasma by dialysis. The intravenous LD 50 of levocarnitine in rats is 5.4 g/kg and the oral LD 50 of levocarnitine in mice is 19.2 g/kg. Large doses of levocarnitine may cause diarrhea.

Si olvidas una dosis

Tómala en cuanto te acuerdes, salvo que falte poco para la siguiente. En ese caso, sáltate la olvidada. Nunca tomes dos dosis a la vez para compensar. Revisa tu prospecto, porque algunos medicamentos son distintos.

From the official U.S. FDA label for this active ingredient. Your pack may have a different strength, so always read its leaflet. If a doctor prescribed it, follow the prescription. Ask a pharmacist if you are unsure. Label dated 2024-12-27.

How much Levocarnitine costs

In other countries

Prices in other countries are not what you will pay where you live; they show how prices compare.

Marcas en todo el mundo

Products with Levocarnitine as the active ingredient. Names differ between countries.

Check your pack of Levocarnitine

Type the registration number on the pack, or scan it with your camera.

O haz fotos de la caja
Te quedan 3 verificaciones gratis hoy Official sources: U.S. FDA · EMA (EU) · Health Canada · WHO alerts

Questions about Levocarnitine

What is Levocarnitine used for?

Levocarnitine oral solution is indicated in the treatment of primary systemic carnitine deficiency. In the reported cases, the clinical presentation consisted of recurrent episodes of Reye-like encephalopathy, hypoketotic hypoglycemia, and/or cardiomyopathy. Associated symptoms included hypotonia, muscle weakness and failure to thrive. A diagnosis of primary carnitine deficiency requires that serum, red cell and/or t (From the official U.S. FDA label.)

How do I take Levocarnitine?

Follow your prescription or the leaflet in your pack. The official label says: For oral use only. Not for parenteral use. Adults: The recommended dosage of levocarnitine is 1 to 3 g/day for a 50 kg subject, which is equivalent to 10 to 30 mL/day of levocarnitine oral solution. Higher doses should be administered only with caution and only where clinical and biochemical considerations make it seem likely that higher doses will be of benefit. Dosage should …

Do I need a prescription for Levocarnitine?

Usually yes. Levocarnitine is a prescription medicine in most countries. Rules differ by country.

What brands contain Levocarnitine?

Levocarnitine is sold under names such as Carni Q-gel Forte, Carnitor. Brand names differ between countries.

What are the side effects of Levocarnitine?

The official label lists: The following adverse reactions associated with the use of oral formulations of levocarnitine were identified in clinical trials or postmarketing reports. Because these reactions were reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency, reliability, or to establish a causal relationship to drug exposure. Gastrointestin… Tell your doctor about any side effect that bothers you or does not go away.

Can children take Levocarnitine?

See DOSAGE AND ADMINISTRATION . Always use the dose for the child's age or weight on the pack or prescription.

Can I take Levocarnitine when pregnant or breastfeeding?

Pregnancy Reproductive studies have been performed in rats and rabbits at doses up to 3.8 times the human dose on the basis of surface area and have revealed no evidence of impaired fertility or harm to the fetus due to levocarnitine. There are, however, no adequate and well-controlled studies in pregnant women. … Ask your doctor or midwife first.

What medicines interact with Levocarnitine?

Reports of INR increase with the use of warfarin have been observed. It is recommended that INR levels be monitored in patients on warfarin therapy after the initiation of treatment with levocarnitine or after dose adjustments. Use the free interaction checker before combining medicines.

What happens if I take too much Levocarnitine?

There have been no reports of toxicity from levocarnitine overdosage. Levocarnitine is easily removed from plasma by dialysis. The intravenous LD 50 of levocarnitine in rats is 5.4 g/kg and the oral LD 50 of levocarnitine in mice is 19.2 g/kg. Large doses of levocarnitine may cause diarrhea. Get medical help right away.

How can I check that my Levocarnitine is genuine?

Scan the registration number on your pack with PillVera (NAFDAC number in Nigeria, NDC in the United States, DIN in Canada), check the expiry date and buy only from licensed pharmacies.

Sources

This page shows what official sources say, in plain words. It is not medical advice: your prescription and your doctor or pharmacist come first. Brand names, strengths and rules differ between countries.