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Oxymetazoline

temporarily relieves nasal congestion due to a cold, hay fever, or other upper respiratory allergies sinus congestion and pressure.

Checked against the official label · Updated

Sold without prescription in some countries Nasal Safety alerts on record

Oxymetazoline: quick answers

Used for
Temporarily relieves nasal congestion due to a cold, hay fever, or other upper respiratory allergies sinus congestion and pressure.
Infancia
Children 6 yrs.
Prescription
Sold without prescription in the United States; rules differ by country.

From the official label (Oct 2025). Your prescription and pharmacist come first.

How to use Oxymetazoline

Lo que dice el prospecto oficial. Si te lo recetó un médico, sigue la receta. Si el prospecto de tu caja es distinto, manda el de tu caja.

Para quién es

Temporarily relieves nasal congestion due to a cold, hay fever, or other upper respiratory allergies sinus congestion and pressure

Cómo tomarlo y con qué frecuencia
  • Remove protective cap
  • Before using for the first time, prime the pump by firmly depressing its rim several times
  • Hold container with thumb at base and nozzle between first and second fingers
  • Without tilting your head, insert nozzle into nostril
  • Fully depress rim with a firm, even stroke and inhale deeply
  • Adults & children 6 yrs. & older (with adult supervision): 2 or 3 sprays in each nostril, not more often than every 10 to 12 hours
  • Do not exceed 2 doses in 24 hours
  • Children 2 to under 6 yrs.: ask a doctor
  • Children under 2 yrs.: do not use
While you are taking it
  • , do not do not exceed recommended dosage do not use this product for more than 3 days
  • Use only as directed
  • Frequent or prolonged use may cause nasal congestion to recur or worsen temporary discomfort such as burning, stinging, sneezing, or increased nasal discharge may occur use of this container by more than one person may spread infection
Talk to a doctor first if

heart disease high blood pressure thyroid disease diabetes trouble urinating due to enlarged prostate gland

Warnings

For external use only; avoid contact with eyes. Do not use by mouth in nostrils on wounds or damaged skin with tight bandages Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes trouble urinating due to enlarged prostate gland When using this product, do not do not exceed recommended dosage do not use this product for more than 3 days. Use only as directed. Frequent or prolonged use may cause nasal congestion to recur or worsen temporary discomfort such as burning, stinging, sneezing, or increased nasal discharge may occur use of this container by more than one person may spread infection Stop use and ask a doctor if symptoms persist. …

Posibles efectos secundarios

Symptoms persist.

Pregnancy and breastfeeding

If pregnant or breast-feeding, ask a health professional before use.

How to store it

Keep out of reach of children.

Si olvidas una dosis

Tómala en cuanto te acuerdes, salvo que falte poco para la siguiente. En ese caso, sáltate la olvidada. Nunca tomes dos dosis a la vez para compensar. Revisa tu prospecto, porque algunos medicamentos son distintos.

From the official U.S. FDA label for this active ingredient. Your pack may have a different strength, so always read its leaflet. If a doctor prescribed it, follow the prescription. Ask a pharmacist if you are unsure. Label dated 2025-10-08.

Registered products

United States (FDA)

Mucinex Sinus-max Severe Congestion Relief Sinus And Allergy Severe Congestion Relief Sinus And AllergyOXYMETAZOLINE HYDROCHLORIDE .05 g/100mL · Solution · Reckitt Benckiser LLC
NDC 63824-120Label
Vicks Sinex Severe CongestionOXYMETAZOLINE HYDROCHLORIDE .0005 g/mL · Spray · Procter & Gamble Manufacturing GmbH
NDC 64336-002Label
Oxymetazoline HydrochlorideOXYMETAZOLINE HYDROCHLORIDE 1 g/g · Powder · Suresource Pharma LLC
NDC 85694-002Label
No Drip Nasal MistOXYMETAZOLINE HYDROCHLORIDE 50 mg/mL · Liquid · Walgreens Company
NDC 0363-2303Label
No Drip Nasal MistOXYMETAZOLINE HYDROCHLORIDE .05 g/100mL · Spray · Kroger Company
NDC 30142-606Label

Other countries: check your pack's registration number and we point you to your regulator.

Safety alerts and recalls

SinuFrin Decongestant (oxymetazoline HCl) Nasal Solution Nasal Decongestant, Decongestant Relief for up to 12 Hours, 12 Hour Relief, 0.5 fl oz (15 ml) bottle, Manufactured by NeilMU.S. FDA Class III
24 Jun 2024 · Neilmed Pharmaceuticals Inc · OngoingSub-potent Drug
Nasal Spray Original No Drip Oxymetazoline HCl Nasal Solution, 12 Hour Pump Mist, 1 FL oz. (30 mL) bottle, a) Quality Choice, Distributed by C.D.M.A. Inc., 43157 W 9 Mile Rd, Novi,U.S. FDA Class II
28 Dec 2023 · Seaway Pharma Inc. · OngoingCGMP Deviations: Firm reported possible microbial contamination in the purified water used in the manufacturing of the products. No contamination was found in the final products.
Lidocaine HCL 2% and Oxymetazoline HCl 0.025% Solution for intranasal administration, 2 mL syringes, Rx only, Compounded by Pine Pharmaceuticals 355 Riverwalk Parkway, Tonawanda, NU.S. FDA Class II
2 Oct 2023 · Pine Pharmaceuticals, LLC · TerminatedLack of Assurance of Sterility
No Drip Nasal Spray, Oxymetazoline HCl 0.05% Nasal Decongestant, 1 FL Oz (30 mL) per bottle, Distributed by SUPERVALU INC., Eden Prairie, MN 55344 USA. NDC 41163-703-10U.S. FDA Class II
26 Oct 2021 · Perrigo Company PLC · TerminatedCGMP Deviations: Products were manufactured with contaminated excipient that was recalled from the excipient supplier.

A recall usually affects certain batches only. Compare the lot number on your pack.

Check your pack of Oxymetazoline

Type the registration number on the pack, or scan it with your camera.

O haz fotos de la caja
Te quedan 3 verificaciones gratis hoy Official sources: U.S. FDA · EMA (EU) · Health Canada · WHO alerts

Questions about Oxymetazoline

What is Oxymetazoline used for?

temporarily relieves nasal congestion due to a cold, hay fever, or other upper respiratory allergies sinus congestion and pressure (From the official U.S. FDA label.)

How do I take Oxymetazoline?

Follow your prescription or the leaflet in your pack. The official label says: Remove protective cap. Before using for the first time, prime the pump by firmly depressing its rim several times. Hold container with thumb at base and nozzle between first and second fingers. Without tilting your head, insert nozzle into nostril. Fully depress rim with a firm, even stroke and inhale deeply. adults & children 6 yrs. & older (with adult supervision): 2 or 3 spr…

How long can I take Oxymetazoline for?

Do not use this product for more than 3 days.

Do I need a prescription for Oxymetazoline?

In many countries Oxymetazoline is sold without a prescription in some strengths. Rules differ by country, so ask a pharmacist.

What brands contain Oxymetazoline?

Oxymetazoline is sold under names such as Sinufrin Plus, Qlearquil Nasal Decongestant, Kovanaze, Rhofade, Afrin, Allerest 12 Hour Nasal Spray, Duramist Plus, Four-way. Brand names differ between countries.

What are the side effects of Oxymetazoline?

The official label lists: symptoms persist. Tell your doctor about any side effect that bothers you or does not go away.

Can children take Oxymetazoline?

The label gives a separate dose by age: children 2 to under. Check the pack or ask a pharmacist.

Can I take Oxymetazoline when pregnant or breastfeeding?

If pregnant or breast-feeding, ask a health professional before use. Ask your doctor or midwife first.

How can I check that my Oxymetazoline is genuine?

Scan the registration number on your pack with PillVera (NAFDAC number in Nigeria, NDC in the United States, DIN in Canada), check the expiry date and buy only from licensed pharmacies.

Sources

This page shows what official sources say, in plain words. It is not medical advice: your prescription and your doctor or pharmacist come first. Brand names, strengths and rules differ between countries.