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Accueil / Médicaments de A à Z / Metronidazole vs Tinidazole

Metronidazole vs Tinidazole

What each one is for, how to take it, side effects and warnings, side by side from the official labels.

MetronidazoleTinidazole
What it isAn antibiotic and antiparasiticNot on the label
Used forSymptomatic Trichomoniasis. Metronidazole tablets are indicated for the treatment of T. vaginalis infection in females and males when the presence of the trichomonad has been confirmed by appropriate laboratory procedures (wet smears and/or cultures). Asymptom…Tinidazole Tablet is a nitroimidazole antimicrobial indicated for: Trichomoniasis ( 1.1 ) Giardiasis: in patients age 3 and older ( 1.2 ) Amebiasis: in patients age 3 and older ( 1.3 ) Bacterial Vaginosis: in adult women ( 1.4, 8.1 ) To reduce the development…
Usual adult doseNot on the labelTreat sexual partners with the same dose and at the same time Giardiasis: Adults: a single 2 g dose taken with food.
ChildrenPediatric patients older than three years of age: 50 mg/kg/day (up to 2 g per day) for 3 days with food.
Prescription (U.S.)YesYes
Common side effectsThe following reactions have been reported during treatment with metronidazole: Central Nervous System: The most serious adverse reactions reported in patients treated with metronidazole have been convulsive seizures, encephalopat…Most common adverse reactions for a single 2 g dose of tinidazole (incidence >1%) are metallic/bitter taste, nausea, weakness/fatigue/malaise, dyspepsia/cramps/epigastric discomfort, vomiting, anorexia, headache, dizziness and con…
Serious warningMetronidazole has been shown to be carcinogenic in mice and rats (see PRECAUTIONS ). Unnecessary use of the drug should be avoided. Its use should be reserved for the conditions described in the INDIC…Carcinogenicity has been seen in mice and rats treated chronically with metronidazole, another nitroimidazole agent [see Nonclinical Toxicology ( 13.1 )]. Although such data have not been reported for…
PregnancyPregnancy: Teratogenic Effects There are no adequate and well controlled studies of metronidazole in pregnant women. There are published data from case-control studies, cohort studies, and 2 meta-anal…8.1 Pregnancy Risk Summary Available published data from a case-control study and case report with Tinidazole Tablets use in pregnant women are insufficient to identify a risk of major birth defects…

From the official U.S. labels. Brands and strengths differ between countries.

Can you take them together?

The official labels mention them together: Although not specifically identified in studies with tinidazole, the following drug interactions were reported for metronidazole, a chemically-related nitroimidazole. Ask a pharmacist before combining them.

Check them together

Questions

What is the difference between Metronidazole and Tinidazole?

Metronidazole is an antibiotic and antiparasitic and Tinidazole is a medicine. Metronidazole is used for: Symptomatic Trichomoniasis. Metronidazole tablets are indicated for the treatment of T. vaginalis infection in females and males when the presence of the trichomonad has been confirmed by appropriate laboratory procedures (wet smears and/or cultures). Asymptom… Tinidazole is used for: Tinidazole Tablet is a nitroimidazole antimicrobial indicated for: Trichomoniasis ( 1.1 ) Giardiasis: in patients age 3 and older ( 1.2 ) Amebiasis: in patients age 3 and older ( 1.3 ) Bacterial Vaginosis: in adult women ( 1.4, 8.1 ) To reduce the development…

Can I take Metronidazole and Tinidazole together?

The official labels mention them together: Although not specifically identified in studies with tinidazole, the following drug interactions were reported for metronidazole, a chemically-related nitroimidazole. Ask a pharmacist before combining them.

Which is better, Metronidazole or Tinidazole?

It depends on what you are treating, your health and other medicines. Your doctor or pharmacist can tell you which one suits you; this page shows what each official label says.