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Silymarin

- for the treatment of acne - reduces the number and severity of acne blemishes and allows skin to heal.

Sold without prescription in some countries Topical Safety alerts on record

How to use Silymarin

What the official label says. If a doctor prescribed it, follow the prescription. Your pack's leaflet comes first if it is different.

Who it is for

- for the treatment of acne - reduces the number and severity of acne blemishes and allows skin to heal

How to take it and how often

- clean the skin thoroughly before applying this product - cover the entire affected area with a thin layer one to three times daily - because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor - if bothersome dryness or peeling occurs, reduce application to once a day or every other day

While you are taking it
  • Skin irritation and dryness is more liekly to occur if you use another topical acne medication at the same time
  • If irritation occurs, only use one topical acne medication at a time
Warnings

For external use only

How to store it

Store in a cool, dark place Keep out of reach of children.

If you miss a dose

Take it when you remember, unless it is nearly time for the next dose. Then skip the missed one. Never take two doses at once to make up for it. Check your leaflet, as some medicines are different.

From the official U.S. FDA label for this active ingredient. Your pack may have a different strength, so always read its leaflet. If a doctor prescribed it, follow the prescription. Ask a pharmacist if you are unsure. Label dated 2023-12-11.

Brands around the world

Products with Silymarin as the active ingredient. Names differ between countries.

Registered products

United States (FDA)

Skinceuticals Silymarin Cf Acne TreatmentSALICYLIC ACID 5 mg/mL · Solution · L'Oreal USA Products Inc
NDC 49967-068Label
Skinceuticals Silymarin Cf Acne Treatment AntioxidantSALICYLIC ACID 5 mg/mL · Solution · Cosmetique Active Production
NDC 69625-069Label

Nigeria (NAFDAC)

NAFDACSilybon 140 Tablets A4-5842

Other countries: check your pack's registration number and we point you to your regulator.

Safety alerts and recalls

Blemish Spot Treatment (Salicylic Acid) 1%, .5 fl oz (15 ml) bottles, Skin Script, Chandler, AZ 85226, UPC 6 10563 13873 9.U.S. FDA Class II
1 Apr 2026 · Island Kinetics, Inc. d.b.a. CoValence Laboratories · OngoingFailed Stability Specifications
Kingskin, SacaCallos, 17% Salicylic acid, 0.5 fl oz (14.8mL) Bottle, Dist. by: Pharmadel LLC, New Castle, DE 19720, Made in India, NDC 55758-423-15, UPC 8 10096 77163 6.U.S. FDA Class II
24 Apr 2025 · KENIL HEALTHCARE PRIVATE LIMITED · TerminatedCGMP Deviations
La Roche-Posay Laboratoire Dermatologique Effaclar Dermatological Acne System, 3 Step Acne Routine Kit, Medicated Gel Cleanser 3.4 fl. oz. (100 mL) Tube, Clarifying Solution 3.4 flU.S. FDA Class II
5 Mar 2025 · L'Oreal USA · OngoingcGMP Deviations: The recall was initiated due to detected trace levels of benzene in a specific lot of this product lot (MYX46W), however out of an abundance of caution, the firm voluntarily recalled all La Roche-Posay Effaclar Duo Dual Action Acne Treatment l
Blemfree All Day Lotion (salicylic acid 0.5% w/w), packaged in a) 1 oz. 29 ML tube NDC:53228-003-01 b) 4 OZ 118ML plastic bottle, UPC 7 01450 90008 6, NDC # 53228-002-01, Equibal LU.S. FDA Class II
26 Jun 2024 · Equibal Inc · TerminatedCGMP Deviations: Manufactured without following Current Good Manufacturing Practises.

A recall usually affects certain batches only. Compare the lot number on your pack.

Check your pack of Silymarin

Or take photos of the pack
3 free checks left today Official sources: U.S. FDA · EMA (EU) · NAFDAC · WHO alerts

Questions about Silymarin

What is Silymarin used for?

- for the treatment of acne - reduces the number and severity of acne blemishes and allows skin to heal (From the official U.S. FDA label.)

How do I take Silymarin?

Follow your prescription or the leaflet in your pack. The official label says: - clean the skin thoroughly before applying this product - cover the entire affected area with a thin layer one to three times daily - because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor - if bothersome dryness or peeling occurs, reduce application to once a da…

Do I need a prescription for Silymarin?

In many countries Silymarin is sold without a prescription in some strengths. Rules differ by country, so ask a pharmacist.

What brands contain Silymarin?

Silymarin is sold under names such as Skinceuticals Silymarin Cf Acne Treatment. Brand names differ between countries.

How can I check that my Silymarin is genuine?

Scan the registration number on your pack with PillVera (NAFDAC number in Nigeria, NDC in the United States, DIN in Canada), check the expiry date and buy only from licensed pharmacies.