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Valsartan vs Irbesartan

What each one is for, how to take it, side effects and warnings, side by side from the official labels.

ValsartanIrbesartan
What it isA blood pressure medicine (ARB)A blood pressure medicine (ARB)
Used forValsartan tablets are an angiotensin II receptor blocker (ARB) indicated for: Hypertension, to lower blood pressure in adults and children 1 year and older. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes…Irbesartan tablets are an angiotensin II receptor blocker (ARB) indicated for: Treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarction…
Usual adult doseIndication Starting Dose Dose Range * Hypertension Adult 80-160 mg once daily 80-320 mg once daily 1-16 years 1 mg/kg once daily Up to 40 mg daily 1-4 mg/kg once daily Up to 160 mg daily Heart Failure 40 mg twice daily 40-160 mg twice daily Post-Myocardial Inf…Not on the label
ChildrenUse of the oral suspension is recommended: in pediatric patients aged 1 to 5 years in patients >5 years of age who cannot swallow tablets and in pediatric patients for whom the calculated dose (mg/kg) does not correspond to the available tablet strengths of va…Not on the label
Prescription (U.S.)YesYes
Common side effectsHypertension: Most common adverse reactions are headache, dizziness, viral infection, fatigue and abdominal pain ( 6.1 ) Heart Failure: Most common adverse reactions are dizziness, hypotension, diarrhea, arthralgia, back pain, fat…The following important adverse reactions are described elsewhere in the labeling: Hypotension in Volume or Salt-Depleted Patients [see Warnings and Precautions (5.2) ] Impaired Renal Function [see Warnings and Precautions (5.3) ]…
Serious warningWhen pregnancy is detected, discontinue valsartan as soon as possible. ( 5.1 ) Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus. ( 5.1 ) WARNI…When pregnancy is detected, discontinue irbesartan tablets as soon as possible [see Warnings and Precautions ( 5.1 ) and Use in Specific Populations ( 8.1 )]. Drugs that act directly on the renin-angi…
PregnancyLactation: Breastfeeding is not recommended ( 8. 2) Pediatrics : Use of valsartan tablets is not recommended in children less than 1 year of age ( 6.1 , 8.4 , 13.2 ) 8.1 Pregnancy Risk Summary Valsart…Lactation: Potential for adverse effects in infants. ( 8.2 ) 8.1 Pregnancy Risk Summary Irbesartan tablets can cause fetal harm when administered to a pregnant woman. Use of drugs that act on the reni…

From the official U.S. labels. Brands and strengths differ between countries.

Can you take them together?

Neither official label mentions the other. That does not prove they are safe together: ask a pharmacist, and use the free interaction checker.

Check them together

Questions

What is the difference between Valsartan and Irbesartan?

Valsartan is a blood pressure medicine (ARB) and Irbesartan is a blood pressure medicine (ARB). Valsartan is used for: Valsartan tablets are an angiotensin II receptor blocker (ARB) indicated for: Hypertension, to lower blood pressure in adults and children 1 year and older. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes… Irbesartan is used for: Irbesartan tablets are an angiotensin II receptor blocker (ARB) indicated for: Treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarction…

Can I take Valsartan and Irbesartan together?

Neither official label mentions the other. That does not prove they are safe together: ask a pharmacist, and use the free interaction checker.

Which is better, Valsartan or Irbesartan?

It depends on what you are treating, your health and other medicines. Your doctor or pharmacist can tell you which one suits you; this page shows what each official label says.