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Amlodipine vs Nifedipine

What each one is for, how to take it, side effects and warnings, side by side from the official labels.

AmlodipineNifedipine
What it isA blood pressure medicine (calcium channel blocker)A blood pressure medicine (calcium channel blocker)
Used foris a calcium channel blocker for the treatment of: Hypertension ( 1.1 ) NORLIQVA is indicated for the treatment of hypertension in adults and children 6 years of age and older, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonf…I. Vasospastic Angina Nifedipine extended-release tablets are indicated for the management of vasospastic angina confirmed by any of the following criteria: 1) classical pattern of angina at rest accompanied by ST segment elevation, 2) angina or coronary arter…
Usual adult doseAdult recommended starting dose: 5 mg orally once daily with a maximum of 10 mg orally once daily.Not on the label
ChildrenPediatric starting dose: 2.5 mg to 5 mg orally once daily.Not on the label
Prescription (U.S.)YesYes
Common side effectsMost common adverse reactions to amlodipine were edema, dizziness, flushing and palpitation which occurred in a dose related manner. Other adverse reactions not clearly dose-related but reported with an incidence >1.0% are fatigue…Over 1000 patients from both controlled and open trials with nifedipine extended-release tablets in hypertension and angina were included in the evaluation of adverse experiences. All side effects reported during nifedipine extend…
Pregnancy8.1 Pregnancy Risk Summary: The limited available data based on post-marketing reports with amlodipine use in pregnant women are not sufficient to inform a drug-associated risk for major birth defects…Not on the label

From the official U.S. labels. Brands and strengths differ between countries.

Can you take them together?

Neither official label mentions the other. That does not prove they are safe together: ask a pharmacist, and use the free interaction checker.

Check them together

Questions

What is the difference between Amlodipine and Nifedipine?

Amlodipine is a blood pressure medicine (calcium channel blocker) and Nifedipine is a blood pressure medicine (calcium channel blocker). Amlodipine is used for: is a calcium channel blocker for the treatment of: Hypertension ( 1.1 ) NORLIQVA is indicated for the treatment of hypertension in adults and children 6 years of age and older, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonf… Nifedipine is used for: I. Vasospastic Angina Nifedipine extended-release tablets are indicated for the management of vasospastic angina confirmed by any of the following criteria: 1) classical pattern of angina at rest accompanied by ST segment elevation, 2) angina or coronary arter…

Can I take Amlodipine and Nifedipine together?

Neither official label mentions the other. That does not prove they are safe together: ask a pharmacist, and use the free interaction checker.

Which is better, Amlodipine or Nifedipine?

It depends on what you are treating, your health and other medicines. Your doctor or pharmacist can tell you which one suits you; this page shows what each official label says.