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Cholestyramine

Cholestyramine is a brand of Cholestyramine.

1) Cholestyramine for Oral Suspension, USP is indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with.

Checked against the official label · Updated

ز - الأدوية التي تصرف بموجب وصفة طبية Oral Safety alerts on record

Cholestyramine: quick answers

Used for
1) Cholestyramine for Oral Suspension, USP is indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia (elevated low density lipoprotein [LDL] cholesterol) who do not respond adequately to diet.
Usual adult dose
Adult dose for Cholestyramine for Oral Suspension, USP is 1 pouch or 1 level scoopful (8.3 grams of Cholestyramine for Oral Suspension, USP contains 4 grams of anhydrous cholestyramine resin) once or twice a day.
Children
? Although an optimal dosage schedule has not been established, standard texts list a usual pediatric dose of 240 mg/kg/day of anhydrous cholestyramine resin in two to three divided doses, normally not to exceed 8 g/day with dose titration based on response an…
Prescription
Prescription medicine in the United States; rules differ by country.

From the official label (Apr 2025). Your prescription and pharmacist come first.

How to use Cholestyramine

ما تقوله النشرة الرسمية. إذا وصفه لك طبيب، فاتبع الوصفة. وإذا اختلفت نشرة عبوتك، فالأولوية لها.

لمن هو

1) Cholestyramine for Oral Suspension, USP is indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia (elevated low density lipoprotein [LDL] cholesterol) who do not respond adequately to diet. Cholestyramine for Oral Suspension, USP may be useful to lower LDL cholesterol in patients who also have hypertriglyceridemia, but it is not indicated where hypertriglyceridemia is the abnormality of most concern. Therapy with lipid-altering agents should be a component of multiple risk factor intervention in those individuals at significantly increased risk for atherosclerotic vascular disease due to hypercholesterolemia. …

كيف يُتناول وكم مرة
  • The recommended starting adult dose for Cholestyramine for Oral Suspension, USP is 1 pouch or 1 level scoopful (8.3 grams of Cholestyramine for Oral Suspension, USP contains 4 grams of anhydrous cholestyramine resin) once or twice a day
  • The recommended maintenance dose for Cholestyramine for Oral Suspension, USP is 2 to 4 pouches or scoopfuls daily (8 to 16 grams anhydrous cholestyramine resin) divided into two doses
  • It is recommended that increases in dose be gradual with periodic assessment of lipid/lipoprotein levels at intervals of not less than 4 weeks
  • The maximum recommended daily dose is 6 pouches or scoopfuls of Cholestyramine for Oral Suspension, USP (24 grams of anhydrous cholestyramine resin)
  • The suggested time of administration is at mealtime but may be modified to avoid interference with absorption of other medications
  • Although the recommended dosing schedule is twice daily, Cholestyramine for Oral Suspension, USP may be administered in 1 to 6 doses per day
  • Cholestyramine for Oral Suspension, USP should not be taken in its dry form
  • Always mix the dry powder with water or other fluids before ingesting
  • See Preparation Instructions
  • Concomitant Therapy Preliminary evidence suggests that the lipid-lowering effects of cholestyramine on total and LDL-cholesterol are enhanced when combined with a HMG-CoA reductase inhibitor, e.g., pravastatin, lovastatin, simvastatin and fluvastatin
  • Additive effects on LDL-cholesterol are also seen with combined nicotinic acid/cholestyramine therapy. …
Children
  • Although an optimal dosage schedule has not been established, standard texts list a usual pediatric dose of 240 mg/kg/day of anhydrous cholestyramine resin in two to three divided doses, normally not to exceed 8 g/day with dose titration based on response and tolerance
  • In calculating pediatric dosages, 48.2 mg of anhydrous cholestyramine resin are contained in 100 mg of Cholestyramine for Oral Suspension, USP
  • The effects of long-term drug administration, as well as its effect in maintaining lowered cholesterol levels
  • In pediatric patients, are unknown
  • Also, see ADVERSE REACTIONS
While you are taking it
  • Inform your physician if you are pregnant or plan to become pregnant or are breast-feeding
  • Drink plenty of fluids and mix each 8.3 gram dose of Cholestyramine for Oral Suspension, USP in at least 2 to 6 ounces of fluid before taking
  • Sipping or holding the resin suspension in the mouth for prolonged periods may lead to changes in the surface of the teeth resulting in discoloration, erosion of enamel or decay, good oral hygiene should be maintained
Talk to a doctor first if

Cholestyramine for Oral Suspension, USP is contraindicated in patients with complete biliary obstruction where bile is not secreted into the intestine and in those individuals who have shown hypersensitivity to any of its components.

Medicines it may not mix with

Cholestyramine resin may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic) or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins and digitalis. Interference with the absorption of oral phosphate supplements has been observed with another positively-charged bile acid sequestrant. Cholestyramine resin may interfere with the pharmacokinetics of drugs that undergo enterohepatic circulation. …

Warnings

PRECAUTIONS General Chronic use of cholestyramine resin may be associated with increased bleeding tendency due to hypoprothrombinemia associated with Vitamin K deficiency. This will usually respond promptly to parenteral Vitamin K 1 and recurrences can be prevented by oral administration of Vitamin K 1 . Reduction of serum or red cell folate has been reported over long term administration of cholestyramine resin. Supplementation with folic acid should be considered in these cases. There is a possibility that prolonged use of cholestyramine resin, since it is a chloride form of anion exchange resin, may produce hyperchloremic acidosis. …

الآثار الجانبية المحتملة

The most common adverse reaction is constipation. When used as a cholesterol-lowering agent predisposing factors for most complaints of constipation are high dose and increased age (more than 60 years old). Most instances of constipation are mild, transient and controlled with conventional therapy. Some patients require a temporary decrease in dosage or discontinuation of therapy. …

Pregnancy and breastfeeding

Pregnancy Pregnancy Category C There are no adequate and well controlled studies in pregnant women. The use of cholestyramine in pregnancy or lactation or by women of childbearing age requires that the potential benefits of drug therapy be weighed against the possible hazards to the mother and child. …

If you take too much

Overdosage of cholestyramine resin has been reported in a patient taking 150% of the maximum recommended daily dosage for a period of several weeks. No ill effects were reported. Should an overdosage occur, the chief potential harm would be obstruction of the gastrointestinal tract. The location of such potential obstruction, the degree of obstruction and the presence or absence of normal gut motility would determine treatment.

How to store it

Storage Store at 20°C to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. Always replace plastic lid after using. KEEP OUT OF THE REACH OF CHILDREN.

إذا نسيت جرعة

تناولها عندما تتذكر، إلا إذا اقترب موعد الجرعة التالية. عندها تخطَّ الجرعة المنسية. لا تتناول جرعتين معًا أبدًا للتعويض. راجع النشرة، فبعض الأدوية مختلفة.

From the official U.S. FDA label for this active ingredient. Your pack may have a different strength, so always read its leaflet. If a doctor prescribed it, follow the prescription. Ask a pharmacist if you are unsure. Label dated 2025-04-17.

Same medicine, other brands

Products with Cholestyramine as the active ingredient. Names differ between countries.

Registered products

United States (FDA)

CholestyramineCHOLESTYRAMINE 4 g/9g · Powder, For Suspension · AiPing Pharmaceutical, Inc.
NDC 11788-150Label
Cholestyramine ResinCHOLESTYRAMINE 100 g/100g · Powder · VALENS PHARMACHEM PRIVATE LIMITED
NDC 87070-001Label
Cholestyramine LightCHOLESTYRAMINE 4 g/4.8g · Powder, For Suspension · TAGI Pharma, Inc.
NDC 51224-009Label
CholestyramineCHOLESTYRAMINE 4 g/8.3g · Powder, For Suspension · TAGI Pharma, Inc.
NDC 51224-011Label
PrevaliteCHOLESTYRAMINE 4 g/5.5g · Powder, For Suspension · Upsher-Smith Laboratories, LLC
NDC 0245-0036Label

Other countries: check your pack's registration number and we point you to your regulator.

Safety alerts and recalls

Cholestyramine active pharmaceutical ingredient packaged in varying grams or kg in bags or drums, Attix Pharmaceuticals, 184 Front Street East, Unit 801, Toronto, Ontario M5A 4N3, U.S. FDA Class II
14 Nov 2014 · Attix Pharmaceuticals · TerminatedPenicillin Cross Contamination: All lots of all products repackaged and distributed between 01/05/12 and 02/12/15 are being recalled because they were repackaged in a facility with penicillin products without adequate separation which could introduce the poten

A recall usually affects certain batches only. Compare the lot number on your pack.

Check your pack of Cholestyramine

Type the registration number on the pack, or scan it with your camera.

أو التقط صورًا للعبوة
تبقّت 3 عمليات تحقق مجانية اليوم Official sources: U.S. FDA · EMA (EU) · Health Canada · WHO alerts

Questions about Cholestyramine

What is in Cholestyramine?

Cholestyramine contains Cholestyramine. Other brands with the same active ingredient work the same way; the dose and strength on your pack are what matter.

What is Cholestyramine used for?

1) Cholestyramine for Oral Suspension, USP is indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia (elevated low density lipoprotein [LDL] cholesterol) who do not respond adequately to diet. Cholestyramine for Oral Suspension, USP may be useful to lower LDL cholesterol in patients who also have hypertriglyceridemia, but it is not indicat (From the official U.S. FDA label.)

How do I take Cholestyramine?

Follow your prescription or the leaflet in your pack. The official label says: The recommended starting adult dose for Cholestyramine for Oral Suspension, USP is 1 pouch or 1 level scoopful (8.3 grams of Cholestyramine for Oral Suspension, USP contains 4 grams of anhydrous cholestyramine resin) once or twice a day. The recommended maintenance dose for Cholestyramine for Oral Suspension, USP is 2 to 4 pouches or scoopfuls daily (8 to 16 grams anhydrous cho…

Can I take Cholestyramine while breastfeeding?

Do I need a prescription for Cholestyramine?

Usually yes. Cholestyramine is a prescription medicine in most countries. Rules differ by country.

What brands contain Cholestyramine?

Cholestyramine is sold under names such as Questran, Prevalite. Brand names differ between countries.

What are the side effects of Cholestyramine?

The official label lists: The most common adverse reaction is constipation. When used as a cholesterol-lowering agent predisposing factors for most complaints of constipation are high dose and increased age (more than 60 years old). Most instances of constipation are mild, transient and controlled with conventional therapy. Some patients require a temporary decrease in dosage or discontinuation of thera… Tell your doctor about any side effect that bothers you or does not go away.

Can children take Cholestyramine?

Although an optimal dosage schedule has not been established, standard texts (6,7) list a usual pediatric dose of 240 mg/kg/day of anhydrous cholestyramine resin in two to three divided doses, normally not to exceed 8 g/day with dose titration based on response and tolerance. In calculating pediatric dosages, 48.2 mg of anhydrous cholestyramine resin are contained in 100 mg of… Always use the dose for the child's age or weight on the pack or prescription.

Can I take Cholestyramine when pregnant or breastfeeding?

Pregnancy Pregnancy Category C There are no adequate and well controlled studies in pregnant women. The use of cholestyramine in pregnancy or lactation or by women of childbearing age requires that the potential benefits of drug therapy be weighed against the possible hazards to the mother and child. … Ask your doctor or midwife first.

What medicines interact with Cholestyramine?

Cholestyramine resin may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic) or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins and digitalis. Interference with the absorption of oral phosphate supplements has been obser… Use the free interaction checker before combining medicines.

What happens if I take too much Cholestyramine?

Overdosage of cholestyramine resin has been reported in a patient taking 150% of the maximum recommended daily dosage for a period of several weeks. No ill effects were reported. Should an overdosage occur, the chief potential harm would be obstruction of the gastrointestinal tract. The location of… Get medical help right away.

How should I store Cholestyramine?

Storage Store at 20°C to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. Always replace plastic lid after using. KEEP OUT OF THE REACH OF CHILDREN.

How can I check that my Cholestyramine is genuine?

Scan the registration number on your pack with PillVera (NAFDAC number in Nigeria, NDC in the United States, DIN in Canada), check the expiry date and buy only from licensed pharmacies.

Sources

This page shows what official sources say, in plain words. It is not medical advice: your prescription and your doctor or pharmacist come first. Brand names, strengths and rules differ between countries.