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Proparacaine

ALCAINE™ ophthalmic solution is indicated for procedures in which a topical ophthalmic anesthetic is indicated: corneal anesthesia of short duration.

Checked against the official label · Updated

ز - الأدوية التي تصرف بموجب وصفة طبية Ophthalmic Safety alerts on record

How to use Proparacaine

ما تقوله النشرة الرسمية. إذا وصفه لك طبيب، فاتبع الوصفة. وإذا اختلفت نشرة عبوتك، فالأولوية لها.

لمن هو

ALCAINE™ ophthalmic solution is indicated for procedures in which a topical ophthalmic anesthetic is indicated: corneal anesthesia of short duration, e.g. tonometry, gonioscopy, removal of corneal foreign bodies, and for short corneal and conjunctival procedures.

كيف يُتناول وكم مرة
  • Usual Dosage: Removal of foreign bodies and sutures, and for tonometry: 1 to 2 drops (in single instillations) in each eye before operating
  • Short Corneal and Conjunctival Procedures: 1 drop in each eye every 5 to 10 minutes for 5 to 7 doses
  • NOTE: ALCAINE™ (proparacaine hydrochloride ophthalmic solution, USP) 0.5% should be clear to straw-color
  • If the solution becomes darker, discard the solution
Children
  • Safety and effectiveness of proparacaine hydrochloride ophthalmic solution
  • In pediatric patients have been established
  • Use of proparacaine hydrochloride is supported by evidence from adequate and well-controlled studies
  • In adults and children over the age of twelve, and safety information in neonates and other
  • Pediatric patients
Older adults

No overall clinical differences in safety or effectiveness have been observed between the elderly and other adult patients.

Talk to a doctor first if

ALCAINE™ ophthalmic solution should be considered contraindicated in patients with known hypersensitivity to any of the ingredients of this preparation.

Warnings

NOT FOR INJECTION - FOR TOPICAL OPHTHALMIC USE ONLY. Prolonged use of a topical ocular anesthetic is not recommended. It may produce permanent corneal opacification with accompanying visual loss. ALCAINE™ ophthalmic solution is indicated for administration under the direct supervision of a healthcare provider. ALCAINE™ ophthalmic solution is not intended for patient self-administration.

الآثار الجانبية المحتملة

Occasional temporary stinging, burning and conjunctival redness may occur with the use of proparacaine. Corneal edema has been reported following the use of proparacaine. A rare, severe, immediate-type, apparently hyperallergic corneal reaction characterized by acute, intense and diffuse epithelial keratitis, a gray, ground glass appearance, sloughing of large areas of necrotic epithelium, corneal filaments and, sometimes, iritis with descemetitis has been reported. Allergic contact dermatitis from proparacaine with drying and fissuring of the fingertips has also been reported.

Pregnancy and breastfeeding

Pregnancy: Animal reproduction studies have not been conducted with ALCAINE ™ (proparacaine hydrochloride ophthalmic solution, USP) 0.5%. It is also not known whether proparacaine hydrochloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Proparacaine hydrochloride should be administered to a pregnant woman only if clearly needed.

إذا نسيت جرعة

تناولها عندما تتذكر، إلا إذا اقترب موعد الجرعة التالية. عندها تخطَّ الجرعة المنسية. لا تتناول جرعتين معًا أبدًا للتعويض. راجع النشرة، فبعض الأدوية مختلفة.

From the official U.S. FDA label for this active ingredient. Your pack may have a different strength, so always read its leaflet. If a doctor prescribed it, follow the prescription. Ask a pharmacist if you are unsure. Label dated 2026-06-10.

الأسماء التجارية حول العالم

Products with Proparacaine as the active ingredient. Names differ between countries.

Registered products

United States (FDA)

Proparacaine HydrochloridePROPARACAINE HYDROCHLORIDE 5 mg/mL · Solution/ Drops · Sandoz Inc.
NDC 61314-016Label
Proparacaine HydrochloridePROPARACAINE HYDROCHLORIDE 5 mg/mL · Solution/ Drops · Bausch & Lomb Incorporated
NDC 24208-730Label
Proparacaine HydrochloridePROPARACAINE HYDROCHLORIDE 5 mg/mL · Solution/ Drops · Somerset Therapeutics, LLC
NDC 70069-601Label
Proparacaine HydrochloridePROPARACAINE HYDROCHLORIDE 5 mg/mL · Solution/ Drops · NuCare Pharmaceuticals,Inc.
NDC 68071-4368Label
Proparacaine HydrochloridePROPARACAINE HYDROCHLORIDE 5 mg/mL · Solution/ Drops · A-S Medication Solutions
NDC 50090-1923Label

Nigeria (NAFDAC)

NAFDACPrimax Eye Drops B4-2293

Other countries: check your pack's registration number and we point you to your regulator.

Safety alerts and recalls

Proparacaine Hydrochloride Ophthalmic Solution, USP 0.5% (sterile), 15 mL bottle, Rx only, MFG: Bausch & Lomb, NDC 24208-730-06U.S. FDA Class II
11 Sep 2024 · Mckesson Medical-Surgical Inc. Corporate Office · TerminatedTemperature abuse: Products exposed to improper temperature above drug label specifications.
Proparacaine Hydrochloride Ophthalmic Solution, USP 0.5%, 15 mL per bottle, Rx only, Manufactured by: Akorn, Inc., Lake Forest, IL 60045. Distributed By: MWI Boise, ID 83705, NDC:U.S. FDA Class II
13 Oct 2022 · Akorn, Inc. · OngoingCGMP Deviations:
Proparacaine Hydrochloride Ophthalmic Solution, USP 0.5%, 15 mL per dropper bottle, Rx only, Distributed by: Akorn Operating Company LLC, Gurnee, IL 60031 NDC: 17478-263-12U.S. FDA Class II
13 Oct 2022 · Akorn, Inc. · OngoingCGMP Deviations:
Proparacaine Hydrochloride Ophthalmic Solution, USP, 0.5%, 15 mL per dropper bottle, Sterile, Rx Only, Manufactured by: Akorn, Inc., Lake Forest, IL 60045. NDC 17478-263-12U.S. FDA Class III
26 Dec 2019 · Akorn, Inc. · TerminatedChemical contamination; out of specification results obtained for equipment cleaning residue rinse sample

A recall usually affects certain batches only. Compare the lot number on your pack.

Check your pack of Proparacaine

Type the registration number on the pack, or scan it with your camera.

أو التقط صورًا للعبوة
تبقّت 3 عمليات تحقق مجانية اليوم Official sources: U.S. FDA · EMA (EU) · Health Canada · WHO alerts

Questions about Proparacaine

What is Proparacaine used for?

ALCAINE™ ophthalmic solution is indicated for procedures in which a topical ophthalmic anesthetic is indicated: corneal anesthesia of short duration, e.g. tonometry, gonioscopy, removal of corneal foreign bodies, and for short corneal and conjunctival procedures. (From the official U.S. FDA label.)

How do I take Proparacaine?

Follow your prescription or the leaflet in your pack. The official label says: Usual Dosage: Removal of foreign bodies and sutures, and for tonometry: 1 to 2 drops (in single instillations) in each eye before operating. Short Corneal and Conjunctival Procedures: 1 drop in each eye every 5 to 10 minutes for 5 to 7 doses. NOTE: ALCAINE™ (proparacaine hydrochloride ophthalmic solution, USP) 0.5% should be clear to straw-color. If the solution becomes darker,…

Do I need a prescription for Proparacaine?

Usually yes. Proparacaine is a prescription medicine in most countries. Rules differ by country.

What brands contain Proparacaine?

Proparacaine is sold under names such as Alcaine, Flucaine, Fluoracaine. Brand names differ between countries.

What are the side effects of Proparacaine?

The official label lists: Occasional temporary stinging, burning and conjunctival redness may occur with the use of proparacaine. Corneal edema has been reported following the use of proparacaine. A rare, severe, immediate-type, apparently hyperallergic corneal reaction characterized by acute, intense and diffuse epithelial keratitis, a gray, ground glass appearance, sloughing of large areas of necrotic… Tell your doctor about any side effect that bothers you or does not go away.

Can children take Proparacaine?

Safety and effectiveness of proparacaine hydrochloride ophthalmic solution in pediatric patients have been established. Use of proparacaine hydrochloride is supported by evidence from adequate and well-controlled studies in adults and children over the age of twelve, and safety information in neonates and other pediatric patients. Always use the dose for the child's age or weight on the pack or prescription.

Can I take Proparacaine when pregnant or breastfeeding?

Pregnancy: Animal reproduction studies have not been conducted with ALCAINE ™ (proparacaine hydrochloride ophthalmic solution, USP) 0.5%. It is also not known whether proparacaine hydrochloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Proparacaine hydrochloride should be administered to a pregnant woman only if clearly need… Ask your doctor or midwife first.

How can I check that my Proparacaine is genuine?

Scan the registration number on your pack with PillVera (NAFDAC number in Nigeria, NDC in the United States, DIN in Canada), check the expiry date and buy only from licensed pharmacies.

Sources

This page shows what official sources say, in plain words. It is not medical advice: your prescription and your doctor or pharmacist come first. Brand names, strengths and rules differ between countries.