Fluorometholone

Fluorometholone ophthalmic suspension 0.1% is indicated for the treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.

• Shake well before using
• Instill one drop into the conjunctival sac two to four times daily
• During the initial 24 to 48 hours, the dosing frequency may be increased to one application every four hours
• Care should be taken not to discontinue therapy prematurely
• If signs and symptoms fail to improve after two days, the patient should be re-evaluated (see PRECAUTIONS )
• The dosing of fluorometholone ophthalmic suspension 0.1% may be reduced, but care should be taken not to discontinue therapy prematurely
• In chronic conditions, withdrawal of treatment should be carried out by gradually decreasing the frequency of applications

Safety and effectiveness in infants below the age of two years have not been established.

No overall differences in safety or effectiveness have been observed between elderly and younger patients.

• If inflammation or pain persists longer than 48 hours or becomes aggravated, the patient should be advised to discontinue use of the medication and consult a physician
• This product is sterile when packaged
• To prevent contamination, care should be taken to avoid touching the bottle tip to eyelids or to any other surface
• The use of this bottle by more than one person may spread infection
• Keep bottle tightly closed when not in use
• Keep out of the reach of children
• The preservative in fluorometholone ophthalmic suspension, benzalkonium chloride, may be absorbed by soft contact lenses. …

• Fluorometholone ophthalmic suspension 0.1% is contraindicated in most viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also in mycobacterial infection of the eye, and fungal diseases of ocular structures
• Fluorometholone ophthalmic suspension 0.1% is also contraindicated in individuals with known or suspected hypersensitivity to any of the ingredients of this preparation and to other corticosteroids

Prolonged use of corticosteroids may increase intraocular pressure in susceptible individuals, resulting in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision, and in posterior subcapsular cataract formation. Prolonged use may also suppress the host immune response and thus increase the hazard of secondary ocular infections. Various ocular diseases and long-term use of topical corticosteroids have been known to cause corneal and scleral thinning. Use of topical corticosteroids in the presence of thin corneal or scleral tissue may lead to perforation. …

Adverse reactions include, in decreasing order of frequency, elevation of intraocular pressure (IOP) with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation, and delayed wound healing. Although systemic effects are extremely uncommon, there have been rare occurrences of systemic hypercorticoidism after use of topical dermatologic steroids applied to the skin. Corticosteroid-containing preparations have also been reported to cause acute anterior uveitis and perforation of the globe. …

Pregnancy Teratogenic effects Fluorometholone has been shown to be embryocidal and teratogenic in rabbits when administered at low multiples of the human ocular dose. Fluorometholone was applied ocularly to rabbits daily on days 6-18 of gestation, and dose-related fetal loss and fetal abnormalities including cleft palate, deformed rib cage, anomalous limbs and neural abnormalities such as encephalocele, craniorachischisis, and spina bifida were o …

Storage: Store at 2°-25°C (36°-77°F); protect from freezing. Store in an upright position. Revised : 12/20 23 For more information, call 1-800-678-1605 Distributed for: AbbVie Inc. North Chicago, IL 60064 © 2023 AbbVie. All rights reserved. …

Take it when you remember, unless it is nearly time for the next dose. Then skip the missed one. Never take two doses at once to make up for it. Check your leaflet, as some medicines are different.