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Methocarbamol 500 Tablet

NAFDAC Reg. No. A4-100146 · Drug

Registered with NAFDAC. Registration activeAs of 28 October 2026 · synced automatically from official sources.
Product
Methocarbamol 500 Tablet
NAFDAC number
A4-100146
Active ingredient
Methocarbamol
Strength
500 mg
Form
Tablet
Manufacturer
Not listed
Applicant (holder)
First J. Pocco Pharmacy Limited
Approved
2 Dec 2021
Status
Active View on NAFDAC ↗
Registration valid to
1 Dec 2026
WHO alerts
None found
Community reports
None
Times checked
0

What we found

  • Methocarbamol 500 Tablet is on the NAFDAC register with an active registration (A4-100146). A valid number alone does not prove a pack is genuine — counterfeiters copy real numbers, so also check the expiry date, seal and print quality.

Generated automatically from the NAFDAC register, WHO alerts and community data as of today. This is not medical advice. Always follow your doctor or pharmacist.

How to use Methocarbamol 500 Tablet

What the official label says. If a doctor prescribed it, follow the prescription. Your pack's leaflet comes first if it is different.

Who it is for

Methocarbamol tablets, USP are indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions. The mode of action of methocarbamol has not been clearly identified, but may be related to its sedative properties. Methocarbamol does not directly relax tense skeletal muscles in man.

How to take it and how often
  • Methocarbamol tablets, USP, 500 mg – Adults: Initial dosage: 3 tablets q.i.d
  • Maintenance dosage: 2 tablets q.i.d
  • Methocarbamol tablets, USP: 750 mg – Adults: Initial dosage: 2 tablets q.i.d
  • Maintenance dosage: 1 tablet q.4h. or 2 tablets t.i.d
  • Six grams a day are recommended for the first 48 to 72 hours of treatment. (For severe conditions 8 grams a day may be administered)
  • Thereafter, the dosage can usually be reduced to approximately 4 grams a day
Children
  • Safety and effectiveness of Methocarbamol tablets, USP
  • Pediatric patients below the age of 16 have not been established
While you are taking it
  • Patients should be cautioned that methocarbamol may cause drowsiness or dizziness, which may impair their ability to operate motor vehicles or machinery
  • Because methocarbamol may possess a general CNS-depressant effect, patients should be cautioned about combined effects with alcohol and other CNS depressants
Talk to a doctor first if

Methocarbamol tablets, USP are contraindicated in patients hypersensitive to methocarbamol or to any of the tablet components.

Medicines it may not mix with

See Warnings and Precautions for interaction with CNS drugs and alcohol. Methocarbamol may inhibit the effect of pyridostigmine bromide. Therefore, methocarbamol should be used with caution in patients with myasthenia gravis receiving anticholinesterase agents.

Warnings

Since methocarbamol may possess a general CNS depressant effect, patients receiving Methocarbamol tablets, USP should be cautioned about combined effects with alcohol and other CNS depressants. Safe use of Methocarbamol tablets, USP has not been established with regard to possible adverse effects upon fetal development. There have been reports of fetal and congenital abnormalities following in utero exposure to methocarbamol. Therefore, Methocarbamol tablets, USP should not be used in women who are or may become pregnant and particularly during early pregnancy unless in the judgment of the physician the potential benefits outweigh the possible hazards (see Precautions, Pregnancy ). …

Possible side effects

Adverse reactions reported coincident with the administration of methocarbamol include: Body as a whole: Anaphylactic reaction, angioneurotic edema, fever, headache Cardiovascular system: Bradycardia, flushing, hypotension, syncope, thrombophlebitis Digestive system: Dyspepsia, jaundice (including cholestatic jaundice), nausea and vomiting Hemic and lymphatic system: Leukopenia Immune system: Hypersensitivity reactions Nervous system: Amnesia, confusion, diplopia, dizziness or lightheadedness, drowsiness, insomnia, mild muscular incoordination, nystagmus, sedation, seizures (including grand mal), vertigo Skin and special senses: Blurred vision, conjunctivitis, nasal congestion, metallic tast …

Pregnancy and breastfeeding

Pregnancy Teratogenic effects Pregnancy Category C Animal reproduction studies have not been conducted with methocarbamol. It is also not known whether methocarbamol can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Methocarbamol tablets, USP should be given to a pregnant woman only if clearly needed. …

If you take too much

Limited information is available on the acute toxicity of methocarbamol. Overdose of methocarbamol is frequently in conjunction with alcohol or other CNS depressants and includes the following symptoms: nausea, drowsiness, blurred vision, hypotension, seizures, and coma. In post-marketing experience, deaths have been reported with an overdose of methocarbamol alone or in the presence of other CNS depressants, alcohol or psychotropic drugs. Treatment Management of overdose includes symptomatic and supportive treatment. …

How to store it

Store at controlled room temperature, between 20°C and 25°C (68°F and 77°F). [see USP Controlled Room Temperature]. Dispense in tight container.

If you miss a dose

Take it when you remember, unless it is nearly time for the next dose. Then skip the missed one. Never take two doses at once to make up for it. Check your leaflet, as some medicines are different.

From the official U.S. FDA label for this active ingredient. Your pack may have a different strength, so always read its leaflet. If a doctor prescribed it, follow the prescription. Ask a pharmacist if you are unsure. Label dated 2020-08-01.

Label for methocarbamol, the active ingredient registered with NAFDAC.

Check your pack of Methocarbamol 500 Tablet

Add the expiry date on your pack for a full Trust Score.

3 free checks left today Official sources: NAFDAC · WHO · U.S. FDA · Health Canada · NLM

About Methocarbamol 500 Tablet

What is in Methocarbamol 500 Tablet?

Methocarbamol 500 Tablet contains Methocarbamol (500 mg), as tablet, according to its NAFDAC registration record.

Is Methocarbamol 500 Tablet registered with NAFDAC?

Yes. Methocarbamol 500 Tablet is listed on the NAFDAC register under registration number A4-100146, and its registration is active as of 28 October 2026.

Has Methocarbamol 500 Tablet been flagged as fake or recalled?

No WHO falsified or substandard medical product alert currently matches Methocarbamol 500 Tablet in our automatically synced alert list.

How can I check that my pack of Methocarbamol 500 Tablet is genuine?

Run a free authenticity scan with the NAFDAC number A4-100146, your pack's expiry date and batch number to get a Trust Score, compare the pack with the NAFDAC record (ingredient, strength, form, manufacturer), and buy only from licensed pharmacies.

How do I take Methocarbamol 500 Tablet?

Follow your prescription or the leaflet in your pack. The official label says: Methocarbamol tablets, USP, 500 mg – Adults: Initial dosage: 3 tablets q.i.d. Maintenance dosage: 2 tablets q.i.d. Methocarbamol tablets, USP: 750 mg – Adults: Initial dosage: 2 tablets q.i.d. Maintenance dosage: 1 tablet q.4h. or 2 tablets t.i.d. Six grams a day are recommended for the first 48 to 72 hours of treatment. (For severe conditions 8 grams a day may be administered)…

What is Methocarbamol 500 Tablet used for?

Methocarbamol tablets, USP are indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions. The mode of action of methocarbamol has not been clearly identified, but may be related to its sedative properties. Methocarbamol does not directly relax tense skeletal muscles in man. (Summarised from the official U.S. FDA label for methocarbamol. Always follow your doctor or pharmacist.)

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