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Adapalene

Adapalene is a brand of Adapalene.

For the treatment of acne.

Checked against the official label · Updated

Sold without prescription in some countries Topical Safety alerts on record

Adapalene: quick answers

What it is
Retinoid
Used for
For the treatment of acne.
Usual adult dose
Adults and children 12 years of age and older: ▪ use once daily ▪ clean the skin gently and pat dry before applying the product ▪ cover the entire affected area with a thin layer.
Children
Children under 12 years of age: ask a doctor.
Prescription
Sold without prescription in the United States; rules differ by country.

From the official label (Nov 2024). Your prescription and pharmacist come first.

How to use Adapalene

Ce que dit la notice officielle. Si un médecin vous l'a prescrit, suivez l'ordonnance. La notice de votre boîte prime si elle est différente.

Pour qui

For the treatment of acne

Comment le prendre et à quelle fréquence
  • Adults and children 12 years of age and older: ▪ use once daily ▪ clean the skin gently and pat dry before applying the product ▪ cover the entire affected area with a thin layer
  • For example, if your acne is on the face, apply the product to the entire face. ▪ do not use more than one time a day
  • Applying more than directed will not provide faster or better results, but may worsen skin irritation
  • Children under 12 years of age: ask a doctor
While you are taking it

▪ limit sun exposure, including light from tanning beds, and use sunscreen when going outdoors. ▪ do not wax to remove hair in areas where the product has been applied ▪ during the early weeks of use, your acne may appear to worsen before it improves (this is normal); continue using as directed, unless you get irritation that becomes severe ▪ irritation (redness, itching, dryness, burning) is more likely to occur: ▪ in the first few weeks of use ▪ if using more than one topical acne medication a …

Talk to a doctor first if

▪on damaged skin (cuts, abrasions, eczema, sunburn) ▪ if you are allergic to adapalene or any of the ingredients in this product

Warnings

For external use only Do not use ▪on damaged skin (cuts, abrasions, eczema, sunburn) ▪ if you are allergic to adapalene or any of the ingredients in this product If pregnant or breast-feeding, ask a doctor before use. When using this product ▪ limit sun exposure, including light from tanning beds, and use sunscreen when going outdoors. ▪ do not wax to remove hair in areas where the product has been applied ▪ during the early weeks of use, your acne may appear to worsen before it improves (this is normal); continue using as directed, unless you get irritation that becomes severe ▪ irritation (redness, itching, dryness, burning) is more likely to occur: ▪ in the first few weeks of use ▪ if usi …

Effets secondaires possibles

▪ you become pregnant, or are planning to become pregnant while using the product ▪ you have symptoms of an allergic reaction (such as itching, rash, hives, swelling of the lips, eyelids, and shortness of breath) ▪ irritation becomes severe ▪ you see no improvement after 3 months of once daily use

Pregnancy and breastfeeding

If pregnant or breast-feeding, ask a doctor before use.

How to store it

▪ store at room temperature 68° to 77°F ▪ protect from freezing Keep out of reach of children.

En cas d'oubli

Prenez-le dès que vous y pensez, sauf s'il est presque l'heure de la dose suivante. Dans ce cas, sautez la dose oubliée. Ne prenez jamais deux doses à la fois pour compenser. Vérifiez votre notice, certains médicaments font exception.

From the official U.S. FDA label for this active ingredient. Your pack may have a different strength, so always read its leaflet. If a doctor prescribed it, follow the prescription. Ask a pharmacist if you are unsure. Label dated 2024-11-12.

How much Adapalene costs

In other countries

Prices in other countries are not what you will pay where you live; they show how prices compare.

Same medicine, other brands

Products with Adapalene as the active ingredient. Names differ between countries.

Registered products

United States (FDA)

Adapalene And Benzoyl PeroxideADAPALENE 3 mg/g, BENZOYL PEROXIDE 25 mg/g · Gel · Bryant Ranch Prepack
NDC 63629-9322Label
AdapaleneADAPALENE .1 g/100g · Cream · Padagis Israel Pharmaceuticals Ltd
NDC 45802-453Label
Adapalene And Benzoyl PeroxideADAPALENE 3 mg/g, BENZOYL PEROXIDE 25 mg/g · Gel · Zydus Lifesciences Limited
NDC 70771-1716Label
AdapaleneADAPALENE 1 mg/g · Gel · Wal-Mart Stores Inc
NDC 79903-338Label
AdapaleneADAPALENE 1 mg/g · Gel · LOreal USA Products Inc
NDC 49967-354Label

Nigeria (NAFDAC)

NAFDACEpiflin 1 mg Gel A4-101036NAFDACNorbacare Gel 30 g A4-100668

Other countries: check your pack's registration number and we point you to your regulator.

Safety alerts and recalls

CABTREO (clindamycin phosphate, adapalene and benzoyl peroxide) Topical Gel 1.2%/0.15%/3.1%, Not for Oral, Ophthalmic or Intravaginal Use, Rx Only, Net Wt. 50g, Distributed by BausU.S. FDA Class II
12 Feb 2024 · MCKESSON CORPORATION · TerminatedCGMP Deviations: Product was stored outside labeled storage temperature requirements. Product was exposed to controlled room temperature environment instead of remaining refrigerated.
ACNE FREE ADAPALENE GL ACN TRTMT 0.5 OZ SKU 2096518 ACNE FREE TRMINTR 10 SPOT TRTMT 1 OZ SKU 2096507 distributed to specific Family Dollar Stores 04/30/2022 through 06/10/2022.U.S. FDA Class II
23 Jun 2022 · Family Dollar Stores, Llc. · OngoingCGMP Deviations: product held outside appropriate storage temperature conditions.
ADAPALENE 0.1%, BENZOYL PEROXIDE 2.5% GEL, ADAPELENE 0.3%, BENZOYL PEROXIDE 2,5% GEL, AZELAIC ACID 15% CREAM, AZELAIC ACID 20% IN OI FREE CREAM, Rx only, Synergy RX, 4901 Morena BlU.S. FDA Class II
10 Feb 2017 · Synergy Rx · TerminatedLack of Assurance of Sterility: There are also CGMP Deviations.
Adapalene active pharmaceutical ingredient packaged in varying grams or kg in bags or drums, Attix Pharmaceuticals, 184 Front Street East, Unit 801, Toronto, Ontario M5A 4N3, CanadU.S. FDA Class II
14 Nov 2014 · Attix Pharmaceuticals · TerminatedPenicillin Cross Contamination: All lots of all products repackaged and distributed between 01/05/12 and 02/12/15 are being recalled because they were repackaged in a facility with penicillin products without adequate separation which could introduce the poten

A recall usually affects certain batches only. Compare the lot number on your pack.

Check your pack of Adapalene

Type the registration number on the pack, or scan it with your camera.

Ou prenez la boîte en photo
Encore 3 vérifications gratuites aujourd'hui Official sources: U.S. FDA · EMA (EU) · Health Canada · WHO alerts

Questions about Adapalene

What is in Adapalene?

Adapalene contains Adapalene. Other brands with the same active ingredient work the same way; the dose and strength on your pack are what matter.

What is Adapalene used for?

For the treatment of acne (From the official U.S. FDA label.)

How do I take Adapalene?

Follow your prescription or the leaflet in your pack. The official label says: Directions Adults and children 12 years of age and older: ▪ use once daily ▪ clean the skin gently and pat dry before applying the product ▪ cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face. ▪ do not use more than one time a day. Applying more than directed will not provide faster or better results,…

Can I take Adapalene while breastfeeding?

If pregnant or breast-feeding,. Ask your doctor or midwife first.

Do I need a prescription for Adapalene?

In many countries Adapalene is sold without a prescription in some strengths. Rules differ by country, so ask a pharmacist.

What brands contain Adapalene?

Adapalene is sold under names such as Differin, Cabtreo, Differin Epiduo, Epiduo, Neutrogena Adapalene 0.1% Acne Treatment. Brand names differ between countries.

What are the side effects of Adapalene?

The official label lists: ▪ you become pregnant, or are planning to become pregnant while using the product ▪ you have symptoms of an allergic reaction (such as itching, rash, hives, swelling of the lips, eyelids, and shortness of breath) ▪ irritation becomes severe ▪ you see no improvement after 3 months of once daily use Tell your doctor about any side effect that bothers you or does not go away.

Can children take Adapalene?

The label gives a separate dose by age: children 12 years. Check the pack or ask a pharmacist.

Can I take Adapalene when pregnant or breastfeeding?

If pregnant or breast-feeding, ask a doctor before use. Ask your doctor or midwife first.

How should I store Adapalene?

▪ store at room temperature 68° to 77°F ▪ protect from freezing

How can I check that my Adapalene is genuine?

Scan the registration number on your pack with PillVera (NAFDAC number in Nigeria, NDC in the United States, DIN in Canada), check the expiry date and buy only from licensed pharmacies.

Sources

This page shows what official sources say, in plain words. It is not medical advice: your prescription and your doctor or pharmacist come first. Brand names, strengths and rules differ between countries.