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Cyproheptadine

Perennial and seasonal allergic rhinitis, Vasomotor rhinitis, Allergic conjunctivitis due to inhalant allergens and foods. Mild, uncomplicated allergi.

Checked against the official label · Updated

Prescription medicine Oral Safety alerts on record

How to use Cyproheptadine

Ce que dit la notice officielle. Si un médecin vous l'a prescrit, suivez l'ordonnance. La notice de votre boîte prime si elle est différente.

Pour qui

Perennial and seasonal allergic rhinitis, Vasomotor rhinitis, Allergic conjunctivitis due to inhalant allergens and foods. Mild, uncomplicated allergic skin manifestations of urticaria and angioedema. Amelioration of allergic reactions to blood or plasma. Cold urticaria. Dermatographism. As therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have been controlled.

Comment le prendre et à quelle fréquence
  • DOSAGE SHOULD BE INDIVIDUALIZED ACCORDING TO THE NEEDS AND THE RESPONSE OF THE PATIENT
  • Children: The total daily dosage for children may be calculated on the basis of body weight or body area using approximately 0.25 mg/kg/day (0.11 mg/lb/day) or 8 mg per square meter of body surface (8 mg/m 2 )
  • In small children for whom the calculation of the dosage based upon body size is important, it may be necessary to use cyproheptadine syrup to permit accurate dosage
  • Age 2 to 6 years: The usual dose is 2 mg (1/2 tablet) two or three times a day, adjusted as necessary to the size and response of the patient
  • The dose is not to exceed 12 mg a day
  • Age 7 to 14 years: The usual dose is 4 mg (1 tablet) two or three times a day, adjusted as necessary to the size and response of the patient
  • The dose is not to exceed 16 mg a day
  • Adults: The total daily dose for adults should not exceed 0.5 mg/kg/day (0.23 mg/lb/day)
  • The therapeutic range is 4 to 20 mg a day, with the majority of patients requiring 12 to 16 mg, a day
  • An occasional patient may require as much as 32 mg a day for adequate relief
  • It is suggested that dosage be initiated with 4 mg (1 tablet) three times a day and adjusted according to the size and response of the patient
Talk to a doctor first if
  • Newborn or Premature
  • Infants: This drug should not be used in newborn or premature
  • Infants
  • Nursing Mothers: Because of the higher risk of antihistamines for infants generally, and for newborns and prematures in particular, antihistamine therapy is contraindicated in nursing mothers
  • Other Conditions: Hypersensitivity to cyproheptadine and other drugs of similar chemical structure
  • Monoamine oxidase inhibitor therapy (see DRUG INTERACTIONS )
  • Angle-closure glaucoma
  • Stenosing peptic ulcer. …
Warnings

Children - Overdosage of antihistamines, particularly in infants and children, may produce hallucinations, central nervous system depression, convulsions, and death. Antihistamines may diminish mental alertness conversely particularly in the young child they may occasionally produce excitation. CNS Depressants - Antihistamines may have additive effects with alcohol and other CNS depressants, e.g., hypnotics, sedatives, tranquilizers, antianxiety agents. Activities Requiring Mental Alertness - Patients should be warned about engaging in activities requiring mental alertness and motor coordination, such as driving a car or operating machinery. …

Effets secondaires possibles

Adverse reactions which have been reported with the use of antihistamines are as follows: Central Nervous System: Sedation and sleepiness (often transient), dizziness, disturbed coordination, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, paresthesias, neuritis, convulsions, euphoria, hallucinations, hysteria, faintness. Integumentary: Allergic manifestation of rash and edema, excessive perspiration, urticaria, photosensitivity. Special Senses: Acute labyrinthitis, blurred vision, diplopia, vertigo, tinnitus. Cardiovascular: Hypotension, palpitation, tachycardia, extrasystoles, anaphylactic shock. …

Pregnancy and breastfeeding

PREGNANCY Pregnancy Category B: Reproduction studies have been performed in rabbits, mice, and rats at oral or subcutaneous doses up to 32 times the maximum recommended human oral dose and have revealed no evidence of impaired fertility or harm to the fetus due to cyproheptadine. Cyproheptadine has been shown to be fetotoxic in rats when given by intraperitoneal injection in doses four times the maximum recommended human oral dose. …

If you take too much

Antihistamine overdosage reactions may vary from central nervous system depression to stimulation, especially in children. Also, atropine-like signs and symptoms (dry mouth; fixed, dilated pupils; flushing, etc.) as well as gastrointestinal symptoms may occur. If vomiting has not occurred spontaneously, the patient should be induced to vomit with syrup of ipecac. If patient is unable to vomit, perform gastric lavage followed by activated charcoal. Isotonic or 1/2 isotonic saline is the lavage of choice. Precautions against aspiration must be taken, especially in infants and children. …

En cas d'oubli

Prenez-le dès que vous y pensez, sauf s'il est presque l'heure de la dose suivante. Dans ce cas, sautez la dose oubliée. Ne prenez jamais deux doses à la fois pour compenser. Vérifiez votre notice, certains médicaments font exception.

From the official U.S. FDA label for this active ingredient. Your pack may have a different strength, so always read its leaflet. If a doctor prescribed it, follow the prescription. Ask a pharmacist if you are unsure. Label dated 2023-01-27.

Marques dans le monde

Products with Cyproheptadine as the active ingredient. Names differ between countries.

Registered products

United States (FDA)

Cyproheptadine HydrochlorideCYPROHEPTADINE HYDROCHLORIDE 2 mg/5mL · Syrup · Rising Pharma Holdings, Inc.
NDC 64980-504Label
Cyproheptadine HydrochlorideCYPROHEPTADINE HYDROCHLORIDE 1 kg/kg · Powder · Olon S.p.A.
NDC 17337-0553Label
Cyproheptadine HydrochlorideCYPROHEPTADINE HYDROCHLORIDE 4 mg/1 · Tablet · A-S Medication Solutions
NDC 50090-5491Label
Cyproheptadine HydrochlorideCYPROHEPTADINE HYDROCHLORIDE 2 mg/1 · Tablet · PANGEA PHARMACEUTICALS, LLC
NDC 81279-129Label
Cyproheptadine HydrochlorideCYPROHEPTADINE HYDROCHLORIDE 4 mg/1 · Tablet · Zydus Pharmaceuticals USA Inc.
NDC 70710-1110Label

Nigeria (NAFDAC)

NAFDACArpetumin A11-100035NAFDACOraxin Syrup A4-1647NAFDACApitol Syrup A4-4942NAFDACUpfine Caplets A4-8880NAFDACApitol Tablets A4-3376NAFDACApetafast Syrup C4-1198NAFDACBonapet Caplets A4-0699NAFDACApitol Caplets_ A11-100260NAFDACApetadine Syrup A11-1226NAFDACCetopron Tablets 04-4181NAFDACFeptadine Tablet C4-1368NAFDACInkretin Tablets A11-100728

Other countries: check your pack's registration number and we point you to your regulator.

Safety alerts and recalls

Rising, Cyproheptadine Hydrochloride Syrup, 2mg/5 mL, 473 mL (ONE PINT), Rx only, Manufactured for: Rising Pharma Holdings, Inc., East Brunswick, NJ, Manufactured by: Lyne LaboratoU.S. FDA Class II
13 Jul 2026 · Rising Pharma Holding, Inc. · OngoingPresence of Precipitate: medication was crystallizing and particles floating in the bottle
Cyproheptadine Hydrochloride Syrup Oral Solution, USP, 2mg/5mL, 473 mL (16 FL. oz.) bottle, NDC: 39328-044-16, Patrin Pharma, Skokie, IL 60076.U.S. FDA Class II
21 May 2019 · Torrent Pharma Inc · TerminatedcGMP Deviations: Potential product contamination with Burkholderia cepacia (B.cepacia) and Ralstonia pickettii (R. pickettii).
Cyproheptadine Hydrochloride Syrup, Oral Solution USP, 2 mg/5 mL, packaged in an amber glass 473 mL (one pint) bottle with child-resistant screw closure, Rx only, Distributed by: RU.S. FDA Class III
7 Jun 2016 · Lyne Laboratories, Inc. · TerminatedSubpotency: product assayed and found OOS for cyproheptadine

A recall usually affects certain batches only. Compare the lot number on your pack.

Check your pack of Cyproheptadine

Type the registration number on the pack, or scan it with your camera.

Ou prenez la boîte en photo
Encore 3 vérifications gratuites aujourd'hui Official sources: U.S. FDA · EMA (EU) · Health Canada · WHO alerts

Questions about Cyproheptadine

What is Cyproheptadine used for?

Perennial and seasonal allergic rhinitis, Vasomotor rhinitis, Allergic conjunctivitis due to inhalant allergens and foods. Mild, uncomplicated allergic skin manifestations of urticaria and angioedema. Amelioration of allergic reactions to blood or plasma. Cold urticaria. Dermatographism. As therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have bee (From the official U.S. FDA label.)

How do I take Cyproheptadine?

Follow your prescription or the leaflet in your pack. The official label says: DOSAGE SHOULD BE INDIVIDUALIZED ACCORDING TO THE NEEDS AND THE RESPONSE OF THE PATIENT. Children: The total daily dosage for children may be calculated on the basis of body weight or body area using approximately 0.25 mg/kg/day (0.11 mg/lb/day) or 8 mg per square meter of body surface (8 mg/m 2 ). In small children for whom the calculation of the dosage based upon body size is …

Do I need a prescription for Cyproheptadine?

Usually yes. Cyproheptadine is a prescription medicine in most countries. Rules differ by country.

What brands contain Cyproheptadine?

Cyproheptadine is sold under names such as Cyproheptadine Hydrochloride. Brand names differ between countries.

What are the side effects of Cyproheptadine?

The official label lists: Adverse reactions which have been reported with the use of antihistamines are as follows: Central Nervous System: Sedation and sleepiness (often transient), dizziness, disturbed coordination, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, paresthesias, neuritis, convulsions, euphoria, hallucinations, hysteria, faintness. Integumentary: Allergi… Tell your doctor about any side effect that bothers you or does not go away.

Can I take Cyproheptadine when pregnant or breastfeeding?

Pregnancy Category B: Reproduction studies have been performed in rabbits, mice, and rats at oral or subcutaneous doses up to 32 times the maximum recommended human oral dose and have revealed no evidence of impaired fertility or harm to the fetus due to cyproheptadine. Cyproheptadine has been shown to be fetotoxic in rats when given by intraperitoneal injection in doses four t… Ask your doctor or midwife first.

Can I drink alcohol with Cyproheptadine?

The official label says: CNS Depressants - Antihistamines may have additive effects with alcohol and other CNS depressants, e.

What happens if I take too much Cyproheptadine?

Antihistamine overdosage reactions may vary from central nervous system depression to stimulation, especially in children. Also, atropine-like signs and symptoms (dry mouth; fixed, dilated pupils; flushing, etc.) as well as gastrointestinal symptoms may occur. If vomiting has not occurred spontaneou… Get medical help right away.

How can I check that my Cyproheptadine is genuine?

Scan the registration number on your pack with PillVera (NAFDAC number in Nigeria, NDC in the United States, DIN in Canada), check the expiry date and buy only from licensed pharmacies.

Sources

This page shows what official sources say, in plain words. It is not medical advice: your prescription and your doctor or pharmacist come first. Brand names, strengths and rules differ between countries.