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Home / Medicines A–Z / Acetaminophen and Codeine

Acetaminophen and Codeine

Acetaminophen and Codeine is a brand of Acetaminophen.

temporarily relieves minor aches and pains due to: headache the common cold backache minor pain of arthritis toothache muscular aches premenstrual and.

Checked against the official label · Updated

Controlled medicine Oral Safety alerts on record
Controlled medicine: CodeinePrescription only. A licensed pharmacist may sell it only against a doctor's prescription.

Codeine · Opioid painkiller / cough medicine · UN 1961 Schedule II

Note: Codeine cough syrups have been banned in Nigeria since May 2018 (production and import). Codeine tablets remain prescription-only.

  • Addiction and dependence, even when taken as prescribed
  • Slow or stopped breathing, especially with alcohol or sleeping pills
  • Overdose can kill: blue lips, pinpoint pupils, cannot be woken. Call for help at once
A shop sold it to you without a prescription, or you are struggling to stop? Emergency: call your local emergency number: 112 / 911 / 999About controlled medicines

How to use Acetaminophen and Codeine

What the official label says. If a doctor prescribed it, follow the prescription. Your pack's leaflet comes first if it is different.

Who it is for

Temporarily relieves minor aches and pains due to: headache the common cold backache minor pain of arthritis toothache muscular aches premenstrual and menstrual cramps temporarily reduces fever

How to take it and how often
  • Do not take more than directed
  • Adults and children 12 years and over take 2 gelcaps every 6 hours while symptoms last
  • Do not take more than 6 gelcaps in 24 hours, unless directed by a doctor
  • Do not take for more than 10 days unless directed by a doctor
  • Children under 12 years: ask a doctor
Talk to a doctor first if

liver disease.

Warnings

Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Do not use if you are allergic to acetaminophen or any of the inactive ingredients in this product with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. …

Possible side effects

New symptoms occur pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days redness or swelling is present These could be signs of a serious condition.

Pregnancy and breastfeeding

If pregnant or breast-feeding, ask a health professional before use.

How to store it

Store at 25°C (77°F); excursions permitted between 15°-30°C (59°-86°F) avoid high humidity see end flap for expiration date and lot number Keep out of reach of children.

If you miss a dose

Take it when you remember, unless it is nearly time for the next dose. Then skip the missed one. Never take two doses at once to make up for it. Check your leaflet, as some medicines are different.

From the official U.S. FDA label for this active ingredient. Your pack may have a different strength, so always read its leaflet. If a doctor prescribed it, follow the prescription. Ask a pharmacist if you are unsure. Label dated 2026-01-02.

Registered products

United States (FDA)

Acetaminophen And Codeine PhosphateACETAMINOPHEN 300 mg/1, CODEINE PHOSPHATE 30 mg/1 · Tablet · Bryant Ranch Prepack
NDC 63629-5666Label
Acetaminophen And Codeine PhosphateACETAMINOPHEN 300 mg/1, CODEINE PHOSPHATE 30 mg/1 · Tablet · NuCare Pharmaceuticals,Inc.
NDC 68071-4673Label
Acetaminophen And Codeine PhosphateACETAMINOPHEN 300 mg/1, CODEINE PHOSPHATE 60 mg/1 · Tablet · Bryant Ranch Prepack
NDC 63629-1190Label
Acetaminophen And Codeine PhosphateACETAMINOPHEN 300 mg/1, CODEINE PHOSPHATE 30 mg/1 · Tablet · Bryant Ranch Prepack
NDC 71335-1818Label
Acetaminophen And Codeine PhosphateACETAMINOPHEN 300 mg/1, CODEINE PHOSPHATE 60 mg/1 · Tablet · Preferred Pharmaceuticals Inc.
NDC 68788-8882Label

Other countries: check your pack's registration number and we point you to your regulator.

Safety alerts and recalls

Oxycodone and Acetaminophen CII Tablets USP, 10mg/325 mg, 100 tablets, Rx only, SpecGx LLC, Webster Groves, MO 63119, NDC 0406-0523-01.U.S. FDA Class II
16 Dec 2025 · SpecGx, LLC · OngoingFailed Tablet/Capsule Specification: There is a potential for the imprint to be missing on tablets.
Oxycodone and Acetaminophen CII Tablets USP, 7.5 mg/325 mg, 100 tablets, Rx only, SpecGx LLC, Webster Groves, MO 63119, NDC 0406-0522-01. Case label: SpecGx LLC, NDC 0406052201, EU.S. FDA Class II
16 Dec 2025 · SpecGx, LLC · OngoingFailed Tablet/Capsule Specification: There is a potential for the imprint to be missing on tablets.
Acetaminophen 500mg Caffeine 65mg caplets, packaged as 2 caplets per packet further packaged in a 50-count box, AERO TAB, Manufactured for AERO HEALTHCARE US, Valley-Cottage, NY, 1U.S. FDA Class II
17 Oct 2025 · Aero Healthcare · OngoingLabeling: Label Mix-up. This issue affects the outer box labeling only. The box incorrectly states the ingredients Acetaminophen 500mg and Caffeine 65mg. The inner pouch correctly states the ingredients are Aspirin (NSAID)*500mg and Caffeine 32.5mg.
TYLENOL, Acetaminophen, Extra Strength, 24 Caplets, 500mg each, distributed by: Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division, Fort Washington, PA 19034, NDCU.S. FDA Class II
21 Oct 2025 · Kenvue Brands LLC · OngoingDefective Container

A recall usually affects certain batches only. Compare the lot number on your pack.

Check your pack of Acetaminophen and Codeine

Type the registration number on the pack, or scan it with your camera.

Or take photos of the pack
3 free checks left today Official sources: U.S. FDA · EMA (EU) · Health Canada · WHO alerts

Questions about Acetaminophen and Codeine

What is in Acetaminophen and Codeine?

Acetaminophen and Codeine contains Acetaminophen. Other brands with the same active ingredient work the same way; the dose and strength on your pack are what matter.

What is Acetaminophen and Codeine used for?

temporarily relieves minor aches and pains due to: headache the common cold backache minor pain of arthritis toothache muscular aches premenstrual and menstrual cramps temporarily reduces fever (From the official U.S. FDA label.)

How do I take Acetaminophen and Codeine?

Follow your prescription or the leaflet in your pack. The official label says: do not take more than directed adults and children 12 years and over take 2 gelcaps every 6 hours while symptoms last do not take more than 6 gelcaps in 24 hours, unless directed by a doctor do not take for more than 10 days unless directed by a doctor children under 12 years: ask a doctor…

Do I need a prescription for Acetaminophen and Codeine?

Yes. Prescription only. A licensed pharmacist may sell it only against a doctor's prescription.

What brands contain Acetaminophen and Codeine?

Acetaminophen and Codeine is sold under names such as Little Fevers, Bactimicina, Pamprin Max Formula, Pamprin Multi-symptom, Pamprin Cramp Formula, Percogesic Reformulated Jan 2011, Premsyn Pms, Panadol Pm. Brand names differ between countries.

What are the side effects of Acetaminophen and Codeine?

The official label lists: new symptoms occur pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days redness or swelling is present These could be signs of a serious condition. Tell your doctor about any side effect that bothers you or does not go away.

Can children take Acetaminophen and Codeine?

The label gives a separate dose by age: children 12 years. Check the pack or ask a pharmacist.

Can I take Acetaminophen and Codeine when pregnant or breastfeeding?

If pregnant or breast-feeding, ask a health professional before use. Ask your doctor or midwife first.

Can I drink alcohol with Acetaminophen and Codeine?

The official label says: Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions.

How should I store Acetaminophen and Codeine?

store at 25°C (77°F); excursions permitted between 15°-30°C (59°-86°F) avoid high humidity see end flap for expiration date and lot number

How can I check that my Acetaminophen and Codeine is genuine?

Scan the registration number on your pack with PillVera (NAFDAC number in Nigeria, NDC in the United States, DIN in Canada), check the expiry date and buy only from licensed pharmacies.

Sources

This page shows what official sources say, in plain words. It is not medical advice: your prescription and your doctor or pharmacist come first. Brand names, strengths and rules differ between countries.