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Histamine dihydrochloride

Indications: For the temporary relief of minor aches and pains of muscles and joints, associated with arthritis, simple back aches, strains, bruises.

Checked against the official label · Updated

Sold without prescription in some countries Topical Safety alerts on record

Histamine dihydrochloride: quick answers

Used for
Indications: For the temporary relief of minor aches and pains of muscles and joints, associated with arthritis, simple back aches, strains, bruises, and sprains.
Usual adult dose
Adults and children two-years of age or older: Apply to affected area not more than three to four times daily.
Children
Children under two-years of age: consult a physician.
Prescription
Sold without prescription in the United States; rules differ by country.

From the official label (Nov 2023). Your prescription and pharmacist come first.

How to use Histamine dihydrochloride

What the official label says. If a doctor prescribed it, follow the prescription. Your pack's leaflet comes first if it is different.

Who it is for

Indications: For the temporary relief of minor aches and pains of muscles and joints, associated with arthritis, simple back aches, strains, bruises, and sprains.

How to take it and how often
  • Adults and children two-years of age or older: Apply to affected area not more than three to four times daily
  • Children under two-years of age: consult a physician
Warnings

For external use only. Avoid contact with eyes. If symptoms persist for more than seven days, discontinue use and consult a physician. Keep out of reach of children. If swallowed, consult a physician ASAP. Do not apply to wounds or damaged skin. Do not bandage tightly. If pregnant or breast feeding, contact a physician prior to use.

Pregnancy and breastfeeding

If pregnant or breast feeding, contact a physician prior to use.

How to store it

Keep out of reach of children.

If you miss a dose

Take it when you remember, unless it is nearly time for the next dose. Then skip the missed one. Never take two doses at once to make up for it. Check your leaflet, as some medicines are different.

From the official U.S. FDA label for this active ingredient. Your pack may have a different strength, so always read its leaflet. If a doctor prescribed it, follow the prescription. Ask a pharmacist if you are unsure. Label dated 2023-11-06.

Brands around the world

Products with Histamine dihydrochloride as the active ingredient. Names differ between countries.

Registered products

United States (FDA)

Histaminum HydrochloricumHISTAMINE DIHYDROCHLORIDE 30 [hp_C]/1 · Pellet · SEVENE USA
NDC 76472-1145Label
Histaminum HydrochloricumHISTAMINE DIHYDROCHLORIDE 30 [hp_X]/30[hp_X] · Pellet · Boiron
NDC 0220-2480Label
Guna Hay Fever ReliefSTRYCHNOS NUX-VOMICA SEED 4 [hp_X]/4g, HISTAMINE DIHYDROCHLORIDE 200 [hp_X]/4g, MANGANESE 8 [hp_X]/4g · Pellet · Guna spa
NDC 17089-476Label
Ropana Pain Relief CreamHISTAMINE DIHYDROCHLORIDE .4 mg/mL · Cream · FUSION PAIN SOLUTIONS LLC
NDC 83613-411Label
Seasonal Allergy ReliefONION 6 [hp_X]/1, SODIUM CHLORIDE 6 [hp_X]/1, HISTAMINE DIHYDROCHLORIDE 12 [hp_X]/1 · Tablet, Soluble · Hyland's Inc.
NDC 54973-3012Label

Other countries: check your pack's registration number and we point you to your regulator.

Safety alerts and recalls

Broadway Joe's Pain Cream, (Histamine Dihydrochloride 0.025%), 1500mg CBD Isolate, 1000mg Hempseed oil, 2 oz-jar, Produced for Broadway Joe's, Franklin, TN, 37067, NDC 83088-8120-U.S. FDA Class II
21 Aug 2026 · Lexia LLC · OngoingCGMP Deviations: Potential contamination of raw material
Broadway Joe's Pain Cream, 3000 gm CBD, (Histamine Dihydrochloride 0.025%) (CDB Isolate 3000mg, HempSeed Oil 2000mg),4 oz-jar, Produced for Broadway Joe's, Franklin, TN, 37067, NDCU.S. FDA Class II
21 Aug 2026 · Lexia LLC · OngoingCGMP Deviations: Potential contamination of raw material

A recall usually affects certain batches only. Compare the lot number on your pack.

Check your pack of Histamine dihydrochloride

Type the registration number on the pack, or scan it with your camera.

Or take photos of the pack
3 free checks left today Official sources: U.S. FDA · EMA (EU) · Health Canada · WHO alerts

Questions about Histamine dihydrochloride

What is Histamine dihydrochloride used for?

Indications: For the temporary relief of minor aches and pains of muscles and joints, associated with arthritis, simple back aches, strains, bruises, and sprains. (From the official U.S. FDA label.)

How do I take Histamine dihydrochloride?

Follow your prescription or the leaflet in your pack. The official label says: Adults and children two-years of age or older: Apply to affected area not more than three to four times daily. Children under two-years of age: consult a physician.…

Can I take Histamine dihydrochloride while breastfeeding?

If pregnant or breast feeding, contact a physician prior to use. Ask your doctor or midwife first.

Do I need a prescription for Histamine dihydrochloride?

In many countries Histamine dihydrochloride is sold without a prescription in some strengths. Rules differ by country, so ask a pharmacist.

What brands contain Histamine dihydrochloride?

Histamine dihydrochloride is sold under names such as Alo, Activon Arthritis, Bakers Best Arthritis Pain Relief Cream With Hemp And Lavender. Brand names differ between countries.

Can children take Histamine dihydrochloride?

The label gives a separate dose by age: children two-years. Check the pack or ask a pharmacist.

Can I take Histamine dihydrochloride when pregnant or breastfeeding?

If pregnant or breast feeding, contact a physician prior to use. Ask your doctor or midwife first.

How can I check that my Histamine dihydrochloride is genuine?

Scan the registration number on your pack with PillVera (NAFDAC number in Nigeria, NDC in the United States, DIN in Canada), check the expiry date and buy only from licensed pharmacies.

Sources

This page shows what official sources say, in plain words. It is not medical advice: your prescription and your doctor or pharmacist come first. Brand names, strengths and rules differ between countries.