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Hydrochloride

For the management of manifestations of psychotic disorders. For the treatment of schizophrenia. To control nausea and vomiting. For relief of restles.

Checked against the official label · Updated

MEDICAMENTO SUJEITO A RECEITA MÉDICA Oral Alertas de segurança registados

Hydrochloride: quick answers

Used for
For the management of manifestations of psychotic disorders.
Usual adult dose
ADULTS Adjust dosage to individual and the severity of his condition, recognizing that the milligram for milligram potency relationship among all dosage forms has not been precisely established clinically.
Prescription
Prescription medicine in the United States; rules differ by country.

From the official label (Aug 2026). Your prescription and pharmacist come first.

How to use Hydrochloride

O que diz a bula oficial. Se um médico receitou, siga a receita. Se a bula da sua caixa for diferente, vale a da sua caixa.

Advertência grave: Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Analyses of seventeen placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 to 1.7 times the risk of death in placebo-treated patients. …
Para quem é

For the management of manifestations of psychotic disorders. For the treatment of schizophrenia. To control nausea and vomiting. For relief of restlessness and apprehension before surgery. For acute intermittent porphyria. As an adjunct in the treatment of tetanus. To control the manifestations of the manic type of manic-depressive illness. For relief of intractable hiccups. …

Como tomar e com que frequência
  • ? ADULTS Adjust dosage to individual and the severity of his condition, recognizing that the milligram for milligram potency relationship among all dosage forms has not been precisely established clinically
  • It is important to increase dosage until symptoms are controlled
  • Dosage should be increased more gradually in debilitated or emaciated patients
  • In continued therapy, gradually reduce dosage to the lowest effective maintenance level, after symptoms have been controlled for a reasonable period
  • The 100 mg and 200 mg tablets are for use in severe neuropsychiatric conditions
  • Elderly Patients - In general, dosages in the lower range are sufficient for most
  • Elderly patients
  • Since they appear to be more susceptible to hypotension and neuromuscular reactions, such patients should be observed closely
  • Dosage should be tailored to the individual, response carefully monitored, and dosage adjusted accordingly
  • Dosage should be increased more gradually in elderly patients
  • Psychotic Disorders - Increase dosage gradually until symptoms are controlled
  • Maximum improvement may not be seen for weeks or even months
  • Continue optimum dosage for 2 weeks; then gradually reduce dosage to the lowest effective maintenance level
  • Daily dosage of 200 mg is not unusual
Talk to a doctor first if
  • Do not use in patients with known hypersensitivity to phenothiazines
  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.)
Warnings

Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Chlorpromazine hydrochloride is not approved for the treatment of patients with dementia-related psychosis [see BOXED WARNING] . The extrapyramidal symptoms which can occur secondary to chlorpromazine may be confused with the central nervous system signs of an undiagnosed primary disease responsible for the vomiting, e.g., Reye's syndrome or other encephalopathy. …

Possíveis efeitos colaterais

Note: Some adverse effects of chlorpromazine may be more likely to occur, or occur with greater intensity, in patients with special medical problems, e.g., patients with mitral insufficiency or pheochromocytoma have experienced severe hypotension following recommended doses. Drowsiness: Usually mild to moderate, may occur, particularly during the first or second week, after which it generally disappears. If troublesome, dosage may be lowered. Jaundice: Overall incidence has been low, regardless of indication or dosage. Most investigators conclude it is a sensitivity reaction. Most cases occur between the second and fourth weeks of therapy. …

If you take too much

[See also ADVERSE REACTIONS ] . Symptoms Primarily symptoms of central nervous system depression to the point of somnolence or coma. Hypotension and extrapyramidal symptoms. Other possible manifestations include agitation and restlessness, convulsions, fever, autonomic reactions such as dry mouth and ileus. EKG changes and cardiac arrhythmias. Treatment It is important to determine other medications taken by the patient since multiple drug therapy is common in overdosage situations. Treatment is essentially symptomatic and supportive. Early gastric lavage is helpful. …

Se esquecer uma dose

Tome assim que lembrar, a menos que esteja quase na hora da próxima dose. Nesse caso, pule a dose esquecida. Nunca tome duas doses de uma vez para compensar. Confira a bula, pois alguns medicamentos são diferentes.

From the official U.S. FDA label for this active ingredient. Your pack may have a different strength, so always read its leaflet. If a doctor prescribed it, follow the prescription. Ask a pharmacist if you are unsure. Label dated 2026-08-19.

Marcas pelo mundo

Products with Hydrochloride as the active ingredient. Names differ between countries.

Registered products

United States (FDA)

Buspirone HydrochlorideBUSPIRONE HYDROCHLORIDE 5 mg/1 · Tablet · Advanced Rx Pharmacy of Tennessee, LLC
NDC 80425-0334Label
Jentadueto XrLINAGLIPTIN 2.5 mg/1, METFORMIN HYDROCHLORIDE 1000 mg/1 · Tablet, Film Coated, Extended Release · Boehringer Ingelheim Pharmaceuticals, Inc.
NDC 0597-0270Label
Powerect Max Power Male DelayLIDOCAINE HYDROCHLORIDE 10 mg/mL · Solution · SKINS SEXUAL HEALTH LIMITED
NDC 81923-198Label
Amlodipine Besylate And Benazepril HydrochlorideAMLODIPINE BESYLATE 10 mg/1, BENAZEPRIL HYDROCHLORIDE 20 mg/1 · Capsule · Northwind Health Company, LLC
NDC 82868-041Label
Quality Choice Maximum Strength Nighttime Cold And FluACETAMINOPHEN 325 mg/1, DEXTROMETHORPHAN HYDROBROMIDE 10 mg/1, DOXYLAMINE SUCCINATE 6.25 mg/1 · Capsule, Liquid Filled · Chain Drug Marketing Association, Inc.
NDC 83324-224Label

Nigeria (NAFDAC)

NAFDACPbenz B4-3959NAFDACVitapro 04-2170NAFDACPodrine A4-2704NAFDACStrimax_ A4-100356NAFDACRealflex B4-0599NAFDACCipromax 04-4950NAFDACCiprotor B4-0522NAFDACGlyformin 04-7968NAFDACArpetumin A11-100035NAFDACFestdrine 04-8278NAFDACLifedrine A4-4758NAFDACTetrakris A11-100425

Other countries: check your pack's registration number and we point you to your regulator.

Safety alerts and recalls

Major ChlorproMAZINE Hydrochloride Tablets, USP, 200 mg, 100 Tablets (10x10) blister package, Rx Only, Packaged and Distributed by Major Pharmaceuticals, Indianapolis, IN 46268, USU.S. FDA Class II
12 Sep 2025 · The Harvard Drug Group LLC dba Major Pharmaceuticals and Rugby Laboratories · OngoingCGMP Deviations: Presence of N-Nitroso Desmethyl Chlorpromazine above the recommended intake limit
Major ChlorproMAZINE Hydrochloride Tablets, USP, 50 mg, 100 Tablets, (10x10) blister package, Rx Only, Packaged and Distributed by Major Pharmaceuticals, Indianapolis, IN 46268, USU.S. FDA Class II
12 Sep 2025 · The Harvard Drug Group LLC dba Major Pharmaceuticals and Rugby Laboratories · OngoingCGMP Deviations: Presence of N-Nitroso Desmethyl Chlorpromazine above the recommended intake limit
Major ChlorproMAZINE Hydrochloride Tablets, USP, 25 mg, 100 Tablets (10x10) blister package, Rx Only, Packaged and Distributed by Major Pharmaceuticals, Indianapolis, IN 46268, USAU.S. FDA Class II
12 Sep 2025 · The Harvard Drug Group LLC dba Major Pharmaceuticals and Rugby Laboratories · OngoingCGMP Deviations: Presence of N-Nitroso Desmethyl Chlorpromazine above the recommended intake limit
Major ChlorproMAZINE Hydrochloride Tablets, USP, 25 mg, 50 Tablets (5x10) blister package, Rx Only, Packaged and Distributed by Major Pharmaceuticals, Indianapolis, IN 46268, USA, U.S. FDA Class II
12 Sep 2025 · The Harvard Drug Group LLC dba Major Pharmaceuticals and Rugby Laboratories · OngoingCGMP Deviations: Presence of N-Nitroso Desmethyl Chlorpromazine above the recommended intake limit

A recall usually affects certain batches only. Compare the lot number on your pack.

Check your pack of Hydrochloride

Type the registration number on the pack, or scan it with your camera.

Ou tire fotos da caixa
Restam 3 verificações grátis hoje Official sources: U.S. FDA · EMA (EU) · Health Canada · WHO alerts

Questions about Hydrochloride

What is Hydrochloride used for?

For the management of manifestations of psychotic disorders. For the treatment of schizophrenia. To control nausea and vomiting. For relief of restlessness and apprehension before surgery. For acute intermittent porphyria. As an adjunct in the treatment of tetanus. To control the manifestations of the manic type of manic-depressive illness. For relief of intractable hiccups. … (From the official U.S. FDA label.)

How do I take Hydrochloride?

Follow your prescription or the leaflet in your pack. The official label says: – ADULTS Adjust dosage to individual and the severity of his condition, recognizing that the milligram for milligram potency relationship among all dosage forms has not been precisely established clinically. It is important to increase dosage until symptoms are controlled. Dosage should be increased more gradually in debilitated or emaciated patients. In continued therapy, grad…

Do I need a prescription for Hydrochloride?

Usually yes. Hydrochloride is a prescription medicine in most countries. Rules differ by country.

What brands contain Hydrochloride?

Hydrochloride is sold under names such as Chlorpromazine. Brand names differ between countries.

What are the side effects of Hydrochloride?

The official label lists: Note: Some adverse effects of chlorpromazine may be more likely to occur, or occur with greater intensity, in patients with special medical problems, e.g., patients with mitral insufficiency or pheochromocytoma have experienced severe hypotension following recommended doses. Drowsiness: Usually mild to moderate, may occur, particularly during the first or second week, after whi… Tell your doctor about any side effect that bothers you or does not go away.

What happens if I take too much Hydrochloride?

[See also ADVERSE REACTIONS ] . Symptoms Primarily symptoms of central nervous system depression to the point of somnolence or coma. Hypotension and extrapyramidal symptoms. Other possible manifestations include agitation and restlessness, convulsions, fever, autonomic reactions such as dry mouth an… Get medical help right away.

How can I check that my Hydrochloride is genuine?

Scan the registration number on your pack with PillVera (NAFDAC number in Nigeria, NDC in the United States, DIN in Canada), check the expiry date and buy only from licensed pharmacies.

Sources

This page shows what official sources say, in plain words. It is not medical advice: your prescription and your doctor or pharmacist come first. Brand names, strengths and rules differ between countries.