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Dexamethasone vs Hydrocortisone

What each one is for, how to take it, side effects and warnings, side by side from the official labels.

DexamethasoneHydrocortisone
What it isA steroid (corticosteroid)A steroid (corticosteroid)
Used forA l l ergic States: Control of severe or incapacitating a llergic conditions intractable to adequate trials of conventional treatment in asthma, atopic dermatitis, contact dermatitis, drug hypersensitivity reactions, perennial or seasonal allergic rhinitis, an…• temporarily relieves itching associated with minor skin irritations, inflammation, and rashes due to: • eczema • psoriasis • poison ivy, oak, sumac • insect bites • detergents • jewelry • cosmetics • soaps • seborrheic dermatitis • temporarily relieves exter…
ChildrenIn pediatric patients, the initial dose of dexamethasone may vary depending on the specific disease entity being treated.Children 2 years of age and older: apply to affected area not more than 3 to 4 times daily.
Prescription (U.S.)YesNo (over the counter)
Common side effects(listed alphabetica ll y, under each subsection) The following adverse reactions have been reported with dexamethasone or other corticosteroids: A ll ergic Reactions: Anaphylactoid reaction, anaphylaxis, angioedema. Cardiovascular…• condition worsens • rectal bleeding occurs • symptoms persist for more than 7 days or clear up and occur again within a few days, and do not begin use of any other hydrocortisone product unless you have asked a doctor
PregnancyPregnancy Teratogenic Effects: Pregnancy Category C. Corticosteroids have been shown to be teratogenic in many species when given in doses equivalent to the human dose. Animal studies in which cortico…Not on the label

From the official U.S. labels. Brands and strengths differ between countries.

Can you take them together?

The official labels mention them together: In addition, there have been cases reported in which concomitant use of amphotericin b and hydrocortisone was followed by cardiac enlargement and congestive heart failure. Ask a pharmacist before combining them.

Check them together

Questions

What is the difference between Dexamethasone and Hydrocortisone?

Dexamethasone is a steroid (corticosteroid) and Hydrocortisone is a steroid (corticosteroid). Dexamethasone is used for: A l l ergic States: Control of severe or incapacitating a llergic conditions intractable to adequate trials of conventional treatment in asthma, atopic dermatitis, contact dermatitis, drug hypersensitivity reactions, perennial or seasonal allergic rhinitis, an… Hydrocortisone is used for: • temporarily relieves itching associated with minor skin irritations, inflammation, and rashes due to: • eczema • psoriasis • poison ivy, oak, sumac • insect bites • detergents • jewelry • cosmetics • soaps • seborrheic dermatitis • temporarily relieves exter…

Can I take Dexamethasone and Hydrocortisone together?

The official labels mention them together: In addition, there have been cases reported in which concomitant use of amphotericin b and hydrocortisone was followed by cardiac enlargement and congestive heart failure. Ask a pharmacist before combining them.

Which is better, Dexamethasone or Hydrocortisone?

It depends on what you are treating, your health and other medicines. Your doctor or pharmacist can tell you which one suits you; this page shows what each official label says.