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Glycopyrrolate

Glycopyrrolate is a brand of Glycopyrrolate.

Glycopyrrolate Injection is an anticholinergic indicated: in anesthesia (adult and pediatric patients) for reduction of salivary, tracheobronchial, an.

Checked against the official label · Updated

Prescription medicine Intramuscular Safety alerts on record

Glycopyrrolate: quick answers

Used for
Glycopyrrolate Injection is an anticholinergic indicated: in anesthesia (adult and pediatric patients) for reduction of salivary, tracheobronchial, and pharyngeal secretions, reduction of volume and acidity of gastric secretions, and blockade of cardiac inhibitory reflexes during induction of anesth…
Usual adult dose
: Adults Preanesthetic Medication: 0.004 mg/kg IM, given 30 to 60 minutes prior to the anticipated time of induction of anesthesia Intraoperative Medication: single doses of 0.1 mg IV and repeated, as needed, at intervals of 2 to 3 minutes Reversal of Neuromus…
Children
Patients that are 1 month to 2 years of age may require up to 0.009 mg/kg Intraoperative Medication: 0.004 mg/kg IV, not to exceed 0.1 mg in a single dose and repeated, as needed, at intervals of 2 to 3 minutes Reversal of Neuromuscular Blockade: 0.2 mg IV for…
Prescription
Prescription medicine in the United States; rules differ by country.

From the official label (Oct 2026). Your prescription and pharmacist come first.

How to use Glycopyrrolate

What the official label says. If a doctor prescribed it, follow the prescription. Your pack's leaflet comes first if it is different.

Who it is for

Glycopyrrolate Injection is an anticholinergic indicated: in anesthesia (adult and pediatric patients) for reduction of salivary, tracheobronchial, and pharyngeal secretions, reduction of volume and acidity of gastric secretions, and blockade of cardiac inhibitory reflexes during induction of anesthesia and intubation. intraoperatively to counteract surgically or drug-induced or vagal reflex-associated arrhythmias. for protection against peripheral muscarinic effects of cholinergic agents. ( 1 ) in peptic ulcer (adults) To reduce symptoms of a peptic ulcer as an adjunct to treatment of peptic ulcer when rapid anticholinergic effect is desired or oral medication is not tolerated. …

How to take it and how often
  • Glycopyrrolate injection may be administered intramuscularly (IM), or intravenously (IV) without dilution, in the following indications. : Adults Preanesthetic Medication: 0.004 mg/kg IM, given 30 to 60 minutes prior to the anticipated time of induction of anesthesia Intraoperative Medication: single doses of 0.1 mg IV and repeated, as needed, at intervals of 2 to 3 minutes Reversal of Neuromuscular Blockade: 0.2 mg for each 1 mg of neostigmine or 5 mg of pyridostigmine Peptic Ulcer: 0.1 mg IV or IM at 4-hour intervals, 3 or 4 times daily
  • Pediatric patients Preanesthetic Medication: 0.004 mg/kg IM, given 30 to 60 minutes prior to the anticipated time of induction of anesthesia
  • Patients that are 1 month to 2 years of age may require up to 0.009 mg/kg Intraoperative Medication: 0.004 mg/kg IV, not to exceed 0.1 mg in a single dose and repeated, as needed, at intervals of 2 to 3 minutes Reversal of Neuromuscular Blockade: 0.2 mg IV for each 1 mg of neostigmine or 5 mg of pyridostigmine Peptic Ulcer: Glycopyrrolate injection is not indicated
  • For the treatment of peptic ulcer
  • In pediatric patients NOTE: CONTAINS BENZYL ALCOHOL [see Use in Specific Populations ]
  • Important Dosage and Administration Instructions • Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit. • Glycopyrrolate injection may be administered intramuscularly or intravenously, without dilution. • Do not dilute for IV push. …
Strengths it comes in

Glycopyrrolate Injection, USP is a clear, colorless, solution for injection available as 0.2 mg per mL glycopyrrolate in presentation of 0.2 mg per mL single-dose vials, 0.4 mg per 2 mL (0.2 mg per mL) single-dose vials, 1 mg per 5 mL (0.2 mg per mL) multi-dose vials, and 4 mg per 20 mL (0.2 mg per mL) multi-dose vials. …

While you are taking it
  • Drowsiness or Blurred Vision : Inform patients that glycopyrrolate injection may cause drowsiness or blurred vision
  • Warn patients not to operate a motor vehicle or other machinery or perform hazardous work until these issues resolve [see Warnings and Precautions ]
  • Heat Prostration : Inform patients that in the presence of fever, high environmental temperature and/or during physical exercise, heat prostration can occur with use of anticholinergic agents, including glycopyrrolate injection (due to decreased sweating), particularly in children and the elderly. …
Talk to a doctor first if

Glycopyrrolate injection is contraindicated in: patients with known hypersensitivity to glycopyrrolate injection or any of its inactive ingredients. peptic ulcer patients with the following concurrent conditions: glaucoma; obstructive uropathy (for example, bladder neck obstruction due to prostatic hypertrophy); obstructive disease of the gastrointestinal tract (as in achalasia, pyloroduodenal stenosis, etc.); paralytic ileus, intestinal atony of the elderly or debilitated patient; unstable card …

Medicines it may not mix with

The concurrent use of glycopyrrolate injection with other anticholinergics or medications with anticholinergic activity, such as phenothiazines, antiparkinson drugs, or tricyclic antidepressants, may intensify the antimuscarinic effects and result in an increase in anticholinergic side effects. Concomitant administration of glycopyrrolate injection and potassium chloride in a wax matrix may increase the severity of potassium chloride-induced gastrointestinal lesions as a result of a slower gastrointestinal transit time. Other anticholinergics or drugs with anticholinergic activity : May intensify the antimuscarinic effects and result in an increase in anticholinergic side effects. …

Warnings

Precipitation of Acute Glaucoma : May cause mydriasis and increase intraocular pressure in patients with glaucoma. Advise patients with glaucoma to promptly seek medical care if they experience symptoms of acute angle closure glaucoma. ( 5.1 ) Drowsiness or Blurred Vision : May cause drowsiness or blurred vision. Advise patients not to drive or perform hazardous work until resolved. ( 5.2 ) Heat Prostration : Advise patients to avoid exertion and high environmental temperatures after receiving glycopyrrolate injection. ( 5.3 ) Intestinal Obstruction : Diarrhea may be an early symptom of incomplete intestinal obstruction. Avoid use in patients with diarrhea and ileostomy or colostomy. …

Possible side effects

The following adverse reactions were identified in clinical studies or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Adverse reactions to anticholinergics include xerostomia (dry mouth); urinary hesitancy and retention; blurred vision and photophobia due to mydriasis (dilation of the pupil); cycloplegia; increased ocular tension; tachycardia; palpitation; decreased sweating; loss of taste; headache; nervousness; drowsiness; weakness; dizziness; insomnia; nausea; vomiting; impotence; suppression of lactation …

Pregnancy and breastfeeding

IN SPECIFIC POPULATIONS Pediatric Use : Infants, patients with Down's Syndrome, and pediatric patients with spastic paralysis or brain damage may experience an increased response to anticholinergics, thus increasing the potential for side effects. Large doses may cause hyperexcitability. …

If you take too much

To combat peripheral anticholinergic effects, a quaternary ammonium anticholinesterase such as neostigmine methylsulfate (which does not cross the blood-brain barrier) may be given intravenously in increments of 0.25 mg in adults. This dosage may be repeated every five to ten minutes until anticholinergic overactivity is reversed or up to a maximum of 2.5 mg. Proportionately smaller doses should be used in pediatric patients. Indication for repetitive doses of neostigmine should be based on close monitoring of the decrease in heart rate and the return of bowel sounds. …

If you miss a dose

Take it when you remember, unless it is nearly time for the next dose. Then skip the missed one. Never take two doses at once to make up for it. Check your leaflet, as some medicines are different.

From the official U.S. FDA label for this active ingredient. Your pack may have a different strength, so always read its leaflet. If a doctor prescribed it, follow the prescription. Ask a pharmacist if you are unsure. Label dated 2026-10-19.

Same medicine, other brands

Products with Glycopyrrolate as the active ingredient. Names differ between countries.

Registered products

United States (FDA)

GlycopyrrolateGLYCOPYRROLATE 1 mg/1 · Tablet · Bryant Ranch Prepack
NDC 72162-1477Label
GlycopyrrolateGLYCOPYRROLATE 1 mg/1 · Tablet · Par Health USA, LLC
NDC 49884-065Label
GlycopyrrolateGLYCOPYRROLATE 2 mg/1 · Tablet · Bryant Ranch Prepack
NDC 72162-1478Label
GlycopyrrolateGLYCOPYRROLATE 2 mg/1 · Tablet · Par Health USA, LLC
NDC 49884-066Label
GlycopyrrolateGLYCOPYRROLATE .2 mg/mL · Injection · BE Pharmaceuticals Inc.
NDC 71839-123Label

Other countries: check your pack's registration number and we point you to your regulator.

Safety alerts and recalls

Glycopyrrolate Injection, USP, 1 mg per 5 mL (0.2 mg per mL), 25 x 5 mL fill in a 6.5 mL vial, Rx only, Multiple Dose Vials, Fresenius Kabi, Lake Zurich, IL 60047 NDC Tray: 63323-U.S. FDA Class II
16 Jul 2026 · Fresenius Kabi USA, LLC · OngoingPresence of Particulate Matter: Hair was found in product
Glycopyrrolate Oral Solution, 1 mg/5 mL, delivers 5 mL, Rx only, Pkg: Precision Dose, Inc, S. Beloil, IL 61080, unit-dose oral syringes, NDCs 68094-073-01 (oral syringe) and 68094-U.S. FDA Class II
14 Jul 2026 · Precision Dose Inc. · OngoingFailed Impurities/Degradation Specifications
Glycopyrrolate Oral Solution, 1 mg/5 mL, 16 oz. (473 mL), Rx only, Manufactured by: MSN Pharmaceuticals Inc., Piscataway, NJ 08854, Distributed by: Novadoz Pharmaceuticals LLC, PisU.S. FDA Class III
15 Dec 2025 · NOVADOZ PHARMACEUTICALS LLC · OngoingFailed Impurities/Degradation Specifications
Glycopyrrolate, 1mg per 5mL, (0.2 mg/mL), Single Dose 5 mL syringe, Rx only, Leiters Health, 13796 Compark Blvd, Englewood, CO 80112. NDC 71449-104-11U.S. FDA Class II
31 Mar 2025 · Denver Solutions, LLC DBA Leiters Health · OngoingLack of Assurance of Sterility: Leaking/damaged syringes.

A recall usually affects certain batches only. Compare the lot number on your pack.

Check your pack of Glycopyrrolate

Type the registration number on the pack, or scan it with your camera.

Or take photos of the pack
3 free checks left today Official sources: U.S. FDA · EMA (EU) · Health Canada · WHO alerts

Questions about Glycopyrrolate

What is in Glycopyrrolate?

Glycopyrrolate contains Glycopyrrolate. Other brands with the same active ingredient work the same way; the dose and strength on your pack are what matter.

What is Glycopyrrolate used for?

Glycopyrrolate Injection is an anticholinergic indicated: in anesthesia (adult and pediatric patients) for reduction of salivary, tracheobronchial, and pharyngeal secretions, reduction of volume and acidity of gastric secretions, and blockade of cardiac inhibitory reflexes during induction of anesthesia and intubation. intraoperatively to counteract surgically or drug-induced or vagal reflex-associated arrhythmias. f (From the official U.S. FDA label.)

How do I take Glycopyrrolate?

Follow your prescription or the leaflet in your pack. The official label says: Glycopyrrolate injection may be administered intramuscularly (IM), or intravenously (IV) without dilution, in the following indications. ( 2.1 ): Adults ( 2.2 , 2.3 , 2.4 , 2.5 ) Preanesthetic Medication: 0.004 mg/kg IM, given 30 to 60 minutes prior to the anticipated time of induction of anesthesia Intraoperative Medication: single doses of 0.1 mg IV and repeated, as needed, a…

Can I drive after taking Glycopyrrolate?

Drowsiness or Blurred Vision : May cause drowsiness or blurred vision.

Do I need a prescription for Glycopyrrolate?

Usually yes. Glycopyrrolate is a prescription medicine in most countries. Rules differ by country.

What brands contain Glycopyrrolate?

Glycopyrrolate is sold under names such as Glycate, Robinul, Bevespi, Lonhala, Qbrexza, Glyrx, Breztri, Dartisla. Brand names differ between countries.

What are the side effects of Glycopyrrolate?

The official label lists: The following adverse reactions were identified in clinical studies or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Adverse reactions to anticholinergics include xerostomia (dry mouth); urina… Tell your doctor about any side effect that bothers you or does not go away.

Can I take Glycopyrrolate when pregnant or breastfeeding?

Pediatric Use : Infants, patients with Down's Syndrome, and pediatric patients with spastic paralysis or brain damage may experience an increased response to anticholinergics, thus increasing the potential for side effects. Large doses may cause hyperexcitability. … Ask your doctor or midwife first.

What medicines interact with Glycopyrrolate?

The concurrent use of glycopyrrolate injection with other anticholinergics or medications with anticholinergic activity, such as phenothiazines, antiparkinson drugs, or tricyclic antidepressants, may intensify the antimuscarinic effects and result in an increase in anticholinergic side effects. Concomitant administration of glycopyrrolate injection and potassium chloride in a w… Use the free interaction checker before combining medicines.

What happens if I take too much Glycopyrrolate?

To combat peripheral anticholinergic effects, a quaternary ammonium anticholinesterase such as neostigmine methylsulfate (which does not cross the blood-brain barrier) may be given intravenously in increments of 0.25 mg in adults. This dosage may be repeated every five to ten minutes until anticholi… Get medical help right away.

How can I check that my Glycopyrrolate is genuine?

Scan the registration number on your pack with PillVera (NAFDAC number in Nigeria, NDC in the United States, DIN in Canada), check the expiry date and buy only from licensed pharmacies.

Sources

This page shows what official sources say, in plain words. It is not medical advice: your prescription and your doctor or pharmacist come first. Brand names, strengths and rules differ between countries.